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Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030

2022-08-28Journal article Open access
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dc.contributor.authorZare Jeddi, Maryam
dc.contributor.authorHopf, Nancy B.
dc.contributor.authorLouro, Henriqueta
dc.contributor.authorViegas, Susana
dc.contributor.authorGalea, Karen S.
dc.contributor.authorPasanen-Kase, Robert
dc.contributor.authorSantonen, Tiina
dc.contributor.authorMustieles, Vicente
dc.contributor.authorFernandez, Mariana F.
dc.contributor.authorVerhagen, Hans
dc.contributor.authorBopp, Stephanie K.
dc.contributor.authorAntignac, Jean Philippe
dc.contributor.authorDavid, Arthur
dc.contributor.authorMol, Hans
dc.contributor.authorBarouki, Robert
dc.contributor.authorAudouze, Karine
dc.contributor.authorDuca, Radu-Corneliu
dc.contributor.authorFantke, Peter
dc.contributor.authorScheepers, Paul
dc.contributor.authorGhosh, Manosij
dc.contributor.authorVan Nieuwenhuyse, An
dc.contributor.authorLobo Vicente, Joana
dc.contributor.authorTrier, Xenia
dc.contributor.authorRambaud, Loïc
dc.contributor.authorFillol, Clémence
dc.contributor.authorDenys, Sebastien
dc.contributor.authorConrad, André
dc.contributor.authorKolossa-Gehring, Marike
dc.contributor.authorPaini, Alicia
dc.contributor.authorArnot, Jon
dc.contributor.authorSchulze, Florian
dc.contributor.authorJones, Kate
dc.contributor.authorSepai, Ovnair
dc.contributor.authorAli, Imran
dc.contributor.authorBrennan, Lorraine
dc.contributor.authorBenfenati, Emilio
dc.contributor.authorCubadda, Francesco
dc.contributor.authorMantovani, Alberto
dc.contributor.authorBartonova, Alena
dc.contributor.authorConnolly, Alison
dc.contributor.authorSlobodnik, Jaroslav
dc.contributor.authorBruinen de Bruin, Yuri
dc.contributor.authorvan Klaveren, Jacob
dc.contributor.authorPalmen, Nicole
dc.contributor.authorDirven, Hubert
dc.contributor.authorHusøy, Trine
dc.contributor.authorThomsen, Cathrine
dc.contributor.authorVirgolino, Ana
dc.contributor.authorRöösli, Martin
dc.contributor.authorGant, Tim
dc.contributor.authorvon Goetz, Natalie
dc.contributor.authorBessems, Jos
dc.date.accessioned2022-11-02T14:40:03Z
dc.date.available2022-11-02T14:40:03Z
dc.date.issued2022-08-28
dc.description.abstractHuman biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission’s Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationEnviron Int. 2022 Aug 28;168:107476. doi: 10.1016/j.envint.2022.107476. Online ahead of print.pt_PT
dc.identifier.doi10.1016/j.envint.2022.107476pt_PT
dc.identifier.issn0160-4120
dc.identifier.urihttp://hdl.handle.net/10400.18/8297
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0160412022004032?via%3Dihubpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectHuman Biomonitoringpt_PT
dc.subjectEnvironmental Genotoxicitypt_PT
dc.subjectChemicals Mixturespt_PT
dc.subjectData Governancept_PT
dc.subjectZero Pollution Ambitionpt_PT
dc.subjectOne Substance-one Assessmentpt_PT
dc.subjectCircular Economypt_PT
dc.subjectEuropean Exposure Science Strategypt_PT
dc.subjectEuropept_PT
dc.subjectGenotoxicidade Ambientalpt_PT
dc.titleDeveloping human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage107476pt_PT
oaire.citation.titleEnvironment Internationalpt_PT
oaire.citation.volume168pt_PT
person.familyNameLouro
person.givenNameHenriqueta
person.identifier157627
person.identifier.ciencia-id721D-2BB1-7DB1
person.identifier.orcid0000-0001-9744-7332
person.identifier.scopus-author-id6507971479
rcaap.embargofctAcesso de acordo com política editorial da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication2361a951-8b9a-4b90-92d6-f6384003a242
relation.isAuthorOfPublication.latestForDiscovery2361a951-8b9a-4b90-92d6-f6384003a242

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