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Standardising surveillance of hepatitis E virus infection in the EU/EEA: a review of national practices and suggestions for the way forward

2019-09-19Journal article Restricted access
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dc.contributor.authorAdlhoch, C.
dc.contributor.authorMand'áková, Z.
dc.contributor.authorEthelberg, S.
dc.contributor.authorEpštein, J.
dc.contributor.authorRimhanen-Finne, R.
dc.contributor.authorFigoni, J.
dc.contributor.authorBaylis, S.A.
dc.contributor.authorFaber, M.
dc.contributor.authorMellou, K.
dc.contributor.authorMurphy, N.
dc.contributor.authorO'Gorman, J.
dc.contributor.authorTosti, M.E.
dc.contributor.authorCiccaglione, A.R.
dc.contributor.authorHofhuis, A.
dc.contributor.authorZaaijer, H.
dc.contributor.authorLange, H.
dc.contributor.authorde Sousa, R.
dc.contributor.authorAvellón, A.
dc.contributor.authorSundqvist, L.
dc.contributor.authorSaid, B.
dc.contributor.authorIjaz, S.
dc.date.accessioned2020-04-29T19:36:16Z
dc.date.available2020-04-29T19:36:16Z
dc.date.issued2019-09-19
dc.descriptionFree PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/31590112/
dc.description.abstractBackground: Hepatitis E virus (HEV) infection is not notifiable at EU/EEA level, therefore surveillance relies on national policies only. Between 2005 and 2015, more than 20,000 cases were reported in EU/EEA countries. HEV testing is established in 26 countries and 19 countries sequence HEV viruses. Objective and study design: WHO's European Action plan for viral hepatitis recommends harmonised surveillance objectives and case definitions. ECDC's HEV expert group developed minimal and optimal criteria for national hepatitis E surveillance to support EU/EEA countries in enhancing their capacity and to harmonise methods. Results: The experts agreed that the primary objectives of national surveillance for HEV infections should focus on the basic epidemiology of the disease: to monitor the incidence of acute cases and chronic infections. The secondary objectives should be to describe viral phylotypes or subtypes and to identify potential clusters/outbreaks and possible routes of transmission. Seventeen of 20 countries with existing surveillance systems collect the minimal data set required to describe the epidemiology of acute cases. Eleven countries test for chronic infections. Twelve countries collect data to identify potential clusters/outbreaks and information on possible routes of transmission. Discussion: Overall, the majority of EU/EEA countries collect the suggested data and meet the outlined requirements to confirm an acute case.pt_PT
dc.description.sponsorshipThe work was supported by two service contracts No. ECD.7600 (HEV epidemiological support - NP/2017/OCS/253) and No. ID 5132: Hepatitis B, C, and E in the EU/EEA: monitoring and testing activities. Staff that were involved in the contracts: Esther Aspinall (Glasgow Caledonian University and Health Protection Scotland), Andrew Rideout (NHS Dumfries and Galloway), Chris Biggam (Glasgow Caledonian University), Gill Hawkins (Health Protection Scotland), and Alison Smith-Palmer (Health Protection Scotland).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Clin Virol. 2019 Nov;120:63-67. doi: 10.1016/j.jcv.2019.09.005. Epub 2019 Sep 19pt_PT
dc.identifier.doi10.1016/j.jcv.2019.09.005pt_PT
dc.identifier.issn1386-6532
dc.identifier.urihttp://hdl.handle.net/10400.18/6559
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S1386653219302100?via%3Dihubpt_PT
dc.subjectHepatitis E Viruspt_PT
dc.subjectEU/EEApt_PT
dc.subjectSurveillancept_PT
dc.subjectTestingpt_PT
dc.subjectInfecções Sistémicas e Zoonosespt_PT
dc.titleStandardising surveillance of hepatitis E virus infection in the EU/EEA: a review of national practices and suggestions for the way forwardpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage67pt_PT
oaire.citation.startPage63pt_PT
oaire.citation.titleJournal of Clinical Virologypt_PT
oaire.citation.volume120pt_PT
rcaap.embargofctDe acordo com política editorial da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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