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Publication
Epidemiology of Invasive Haemophilus influenzae Disease, Europe, 2007-2014
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Advisor(s)
Abstract(s)
We describe the epidemiology of invasive Haemophilus influenzae disease during 2007-2014 in 12 European countries and assess overall H. influenzae disease trends by serotype and patient age. Mean annual notification rate was 0.6 cases/100,000 population, with an increasing annual trend of 3.3% (95% CI 2.3% to 4.3%). The notification rate was highest for patients <1 month of age (23.4 cases/100,000 population). Nontypeable H. influenzae (NTHi) caused 78% of all cases and showed increasing trends among persons <1 month and >20 years of age. Serotype f cases showed an increasing trend among persons >60 years of age. Serotype b cases showed decreasing trends among persons 1-5 months, 1-4 years, and >40 years of age. Sustained success of routine H. influenzae serotype b vaccination is evident. Surveillance systems must adopt a broad focus for invasive H. influenzae disease. Increasing reports of NTHi, particularly among neonates, highlight the potential benefit of a vaccine against NTHi.
Description
European Centre for Disease Prevention and Control Country Experts for Invasive Haemophilus influenzae Disease: INSA - Paula Lavado
Keywords
Adolescent Adult Child Child, Preschool Europe Haemophilus Infections Haemophilus influenzae Humans Infant Middle Aged Retrospective Studies Serogroup Young Adult Infecções Respiratórias
Pedagogical Context
Citation
Emerg Infect Dis. 2017 Mar;23(3):396-404. doi: 10.3201/eid2303.161552.
Publisher
Centers for Disease Control and Prevention