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Outdoor air pollution from industrial chemicals causing new onset of asthma or COPD: a systematic review protocol

2020-12-28Journal article Open access
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dc.contributor.authorLux, Harald
dc.contributor.authorBaur, Xaver
dc.contributor.authorBudnik, Lygia Therese
dc.contributor.authorHeutelbeck, Astrid
dc.contributor.authorTeixeira, João Paulo
dc.contributor.authorNeumann, Emeri
dc.contributor.authorAdliene, Diana
dc.contributor.authorPuišo, Judita
dc.contributor.authorLucas, David
dc.contributor.authorLöndahl, Jakob
dc.contributor.authorDamialis, Athanasios
dc.contributor.authorGoksel, Ozlem
dc.contributor.authorOrru, Hans
dc.date.accessioned2021-03-03T16:25:34Z
dc.date.available2021-03-03T16:25:34Z
dc.date.issued2020-12-28
dc.descriptionStudy protocolpt_PT
dc.descriptionTrial registration: This protocol was registered in PROSPERO, registration number CRD42020151573.pt_PT
dc.description.abstractBackground: Until today, industrial sources contribute to the multifaceted contamination of environmental air. Exposure to air pollutants has the potential to initiate and promote asthma and chronic obstructive pulmonary disease (COPD). At global scale, both entities cause the majority of about 4 million annual deaths by respiratory disease. However, we identified industrial contamination as a subgroup of air pollution that may be associated with this burden and is underinvestigated in research. Therefore, the aim of this study is to investigate associations between substances industrially released into environmental air and the occurrence of asthma and COPD in the human population. Here we present the protocol for our systematic review of the current evidence. Methods: The following determinations will be applied during the systematic review process and are specified in the protocol that complies with the PRISMA-P statement. Populations of children and adults, as well as outdoor workers, exposed to industrially released air pollutants are of interest. Eligible studies may include subjects as controls who are non- or less exposed to the investigated air pollutants. The outcomes new-onset asthma and/or COPD investigated with risk ratio, odds ratio, hazard ratio, incidence rate ratio, cumulative incidence, and incidence rate are eligible. We will search the electronic literature databases EMBASE, MEDLINE, and Web of Science for peer-reviewed reports of incidence studies and incidence case-control studies. After systematic sorting of initial records, included studies will be subjected to quality assessment. Data will be synthesized qualitatively and, if appropriate, quantitatively for risk ratio and odds ratio. We will maintain and provide a PRISMA report. Discussion: Results of this systematic review may indicate alterations of incidence and risk of asthma and/or COPD in populations within industrial exposure radiuses including outdoor workplaces. Specific causal substances and compositions will be identified, but results will depend on the exposure assessment of the eligible studies. Our approach covers effects of industrial contributions to overall air pollution if studies reportedly attribute investigated emissions to industry. Results of this study may raise the question wether the available higher-level evidence sufficiently covers the current scale of industrial exposure scenarios and their potential harm to respiratory health.pt_PT
dc.description.sponsorshipThe protocol is part of the systematic review which is funded by EU-COST action DiMoPEx (funding reference number CA-15129; to LTB). The COST action is supported by the EU Framework Program Horizon 2020. HO’s work is supported by the Estonian Ministry of Education and Research Grant IUT34– 17. JL’s contribution is funded within a project by the Swedish Research Council for Health, Working Life and Welfare (FORTE, number 2017–00690). Open Access funding enabled and organized by Projekt DEAL.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Occup Med Toxicol. 2020 Dec 28;15(1):38. doi: 10.1186/s12995-020-00289-6.pt_PT
dc.identifier.doi10.1186/s12995-020-00289-6pt_PT
dc.identifier.issn1745-6673
dc.identifier.urihttp://hdl.handle.net/10400.18/7297
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMCpt_PT
dc.relation.publisherversionhttps://occup-med.biomedcentral.com/articles/10.1186/s12995-020-00289-6pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAir Pollutionpt_PT
dc.subjectChronic Obstructive Pulmonary Diseasept_PT
dc.subjectInhaled Particlespt_PT
dc.subjectOccupational Exposurept_PT
dc.subjectOutdoor Exposurept_PT
dc.subjectRespiratory Diseasept_PT
dc.subjectSystematic Literature Reviewpt_PT
dc.subjectAr e Saúde Ocupacionalpt_PT
dc.titleOutdoor air pollution from industrial chemicals causing new onset of asthma or COPD: a systematic review protocolpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1pt_PT
oaire.citation.startPage38pt_PT
oaire.citation.titleJournal of Occupational Medicine and Toxicologypt_PT
oaire.citation.volume15pt_PT
rcaap.embargofctAcesso de acordo com política editorial da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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