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Monkeypox: From A Neglected Tropical Disease to a Public Health Threat

2022-09-30Journal article Open access
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dc.contributor.authorAntunes, Francisco
dc.contributor.authorCordeiro, Rita
dc.contributor.authorVirgolino, Ana
dc.date.accessioned2023-02-28T11:21:47Z
dc.date.available2023-02-28T11:21:47Z
dc.date.issued2022-09-30
dc.description.abstractSince the first case of human monkeypox was diagnosed in 1970, the disease remained endemic in several countries in West and Central Africa. In 1996, there was a sudden increase in cases in the Democratic Republic of Congo (DRC), and since 2017 an ongoing outbreak in Nigeria took place, probably related to the population growth, human invasion of MPXV animal habitat reservoirs, and the waning of the cross-protection offered from smallpox immunization, later ending in 1980. Since May 2022, an unprecedented outbreak of human monkeypox has rapidly spread around the world, outside endemic regions of Africa, through new modes of transmission, showing differences in clinical features compared with previous reports. The 2022 MPXV strain belongs to the clade of West Africa but diverges from the original strain, making the virus more transmissible. The authors review the main milestones in more than 50 years of history of human monkeypox, from a rare viral zoonotic infection to a public health emergency.pt_PT
dc.description.sponsorshipThe writing of this manuscript received the support of Fundação para a Ciência e a Tecnologia, grant numbers UIDB/04295/2020 and UIDP/04295/2020.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInfect Dis Rep. 2022 Sep 30;14(5):772-783. doi: 10.3390/idr14050079. Reviewpt_PT
dc.identifier.doi10.3390/idr14050079pt_PT
dc.identifier.issn2036-7430
dc.identifier.urihttp://hdl.handle.net/10400.18/8531
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationEnvironmental Health Institute
dc.relationEnvironmental Health Institute
dc.relation.publisherversionhttps://www.mdpi.com/2036-7449/14/5/79pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectMonkeypoxpt_PT
dc.subjectMonkeypox Viruspt_PT
dc.subjectZoonosispt_PT
dc.subjectOutbreakpt_PT
dc.subjectEmerging Infectious Diseasespt_PT
dc.subjectWest Africapt_PT
dc.subjectCentral Africapt_PT
dc.subjectInfecções Sistémicas e Zoonosespt_PT
dc.titleMonkeypox: From A Neglected Tropical Disease to a Public Health Threatpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleEnvironmental Health Institute
oaire.awardTitleEnvironmental Health Institute
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04295%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04295%2F2020/PT
oaire.citation.endPage783pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage772pt_PT
oaire.citation.titleInfectious Disease Reportspt_PT
oaire.citation.volume14pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctAcesso de acordo com política editorial da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication3b07eced-ff53-4cd9-94e3-064261672665
relation.isProjectOfPublication2932272c-f9a3-4271-90b9-39cbdc06e6c7
relation.isProjectOfPublication.latestForDiscovery3b07eced-ff53-4cd9-94e3-064261672665

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