Predominance of influenza A(H3N2) virus genetic subclade 3C.2a1 during an early 2016/17 influenza season in Europe - Contribution of surveillance data from World Health Organization (WHO) European Region to the WHO vaccine composition consultation for northern hemisphere 2017/18

Melidou, Angeliki; Broberg, Eeva; European region influenza surveillance network

Publication

Predominance of influenza A(H3N2) virus genetic subclade 3C.2a1 during an early 2016/17 influenza season in Europe - Contribution of surveillance data from World Health Organization (WHO) European Region to the WHO vaccine composition consultation for northern hemisphere 2017/18

2017-09-05Journal article

dc.contributor.author	Melidou, Angeliki
dc.contributor.author	Broberg, Eeva
dc.contributor.author	European region influenza surveillance network
dc.date.accessioned	2019-03-22T13:58:31Z
dc.date.available	2019-03-22T13:58:31Z
dc.date.issued	2017-09-05
dc.description	European region influenza surveillance Network author lisT - Portugal: Raquel Guiomar, Pedro Pechirra, Paula Cristóvão, Inês Costa, Patricia Conde (National Influenza and Other Respiratory Virus Reference Laboratory, Infectious Diseases Department, National Institute of Health Dr. Ricardo Jorge, Lisbon) and Ana Paula Rodrigues (Department of Epidemiology, National Instituteof Health Dr. Ricardo Jorge, Lisbon)	pt_PT
dc.description	Erratum in: Erratum to "Predominance of influenza A(H3N2) virus genetic subclade 3C.2a1 during an early 2016/17 influenza season in Europe - Contribution of surveillance data from World Health Organization (WHO) European region to the WHO vaccine composition consultation for northern hemisphere 2017/18" [Vaccine 35 (2017) 4828-4835]. [Vaccine. 2018 May 3;36(19):2740-2741. doi: 10.1016/j.vaccine.2017.12.039. Epub 2017 Dec 20]. Disponível em: https://doi.org/10.1016/j.vaccine.2017.12.039	pt_PT
dc.description.abstract	During the European 2016/17 influenza season, A(H3N2) viruses have predominated and the majority clustered in genetic subclade 3C.2a1. Genetic analyses showed that circulating viruses have undergone considerable genetic diversification of the haemagglutinin gene from the current vaccine virus A/Hong Kong/4801/2014 (clade 3C.2a), but the antigenic data that is limited by the challenges with the antigenic characterisation of currently circulating A(H3N2) viruses, showed no clear evidence of antigenic change. The recommended A(H3N2) vaccine component for the northern hemisphere 2017/18 influenza season remained unchanged. However, early and mid-season vaccine effectiveness (VE) estimates were suggestive of reduced VE against A(H3N2) viruses.	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	Vaccine. 2017 Sep 5;35(37):4828-4835. doi: 10.1016/j.vaccine.2017.07.057. Epub 2017 Aug 7	pt_PT
dc.identifier.doi	10.1016/j.vaccine.2017.07.057	pt_PT
dc.identifier.issn	0264-410X
dc.identifier.uri	http://hdl.handle.net/10400.18/6275
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Elsevier	pt_PT
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/pii/S0264410X17309659?via%3Dihub	pt_PT
dc.subject	Europe	pt_PT
dc.subject	Humans	pt_PT
dc.subject	Influenza A Virus, H3N2 Subtype	pt_PT
dc.subject	Influenza Vaccines	pt_PT
dc.subject	Influenza, Human	pt_PT
dc.subject	Lectins	pt_PT
dc.subject	World Health Organization	pt_PT
dc.subject	Infecções Respiratórias	pt_PT
dc.title	Predominance of influenza A(H3N2) virus genetic subclade 3C.2a1 during an early 2016/17 influenza season in Europe - Contribution of surveillance data from World Health Organization (WHO) European Region to the WHO vaccine composition consultation for northern hemisphere 2017/18	pt_PT
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.endPage	4835	pt_PT
oaire.citation.issue	37	pt_PT
oaire.citation.startPage	4828	pt_PT
oaire.citation.title	Vaccine	pt_PT
oaire.citation.volume	35	pt_PT
rcaap.rights	openAccess	pt_PT
rcaap.type	article	pt_PT