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Publicação
Cross-sectional study on protective antibodies against influenza A virus subtypes and cross-protection against influenza A(H3N2) subclade K, Portugal, August 2025
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Orientador(es)
Resumo(s)
The 2025/26 season was marked by co-circulation of influenza A subtypes, with the first detection of A(H3N2) subclade K in September 2025. In August 2025 in Portugal, 14.8% (95% CI: 12.2-17.8) of 886 persons tested had cross-protective antibodies against this subclade. The overall seroprevalence against circulating A(H1N1)pdm09 strains was 28.1% (95% CI: 24.4-32.0). These data highlight the presence of previous cross-reactive antibodies and the possible advantage of vaccination in the extent of detectable antibodies against influenza viruses.
Descrição
Portuguese Laboratory Network for the Diagnosis of Influenza and Respiratory Viruses: João Tiago Guimarães, Maria João Cardoso, Angelica Ramos, Paulo Pereira, Ana Paula Castro, Maria Helena Marques, Paula Mota, Ana Ferreira, Paulo Lopes, Gabriela Abreu, Adriana Pedrosa, Ana Cristina Silva, Póvoa de Varzim, Nádia Sousa Martins, Aurélio Mesquita, Marina Majar, Ana Filipa Calheiros, José António Mota Freitas, Sandra Margarida Vieira, Susana Gomes, Cacilda Magalhães, Maria J Soares, Maria José Montanha, Carlos Vaz, Helena Silva, Ezequiel Moreira, Carla Ferreira, Cristiana Lopes, Fernando Rodrigues, Teresa Reis, Sofia Almeida, Patrícia Amantegui, Tiago Costa, Patrícia Fonseca, Bruno Marques, Carina Moita, Sandra Paulo, Ricardo Rodrigues, José Afonso Rodrigues Moreira, Mariana Fradilha, Mario Cunha, Sofia Seabra, Ana Pires, Sara Correia, Diana Nunes, Cristina Toscano, Ana Paula Dias, Luís Silva, João Luís, Rita Rodrigues, Luisa Sancho, Lucia Coimbra, Elzara Aliyeva, Paula Gama, Jóni Mota, Ana Helena Lopes, Bela Nogueira, Ana Frota, Jéssica Peres, Maria João Ramos, Filomena Caldeira, Carina Rodrigues, Ana Mira, Ana Serrano, Inês Moreira, Paula Barbeiro, Elena Kronberg, Maria Paula Falcão, Alzira Louro, Armindo Gonçalves, Ana Loureiro, Teresa Garcia Rego, Maria Teresa Dias, Ana Rita Couto, Ana Marques, José Alves, Ludivina Freitas, Susana Agostinho.
Palavras-chave
A(H3N2) subclade K Influenza Antibodies Cross-protection Seroprevalence Infecções Respiratórias Cuidados de Saúde Portugal
Contexto Educativo
Citação
Euro Surveill. 2026 Feb;31(6):2600070. doi: 10.2807/1560-7917.ES.2026.31.6.2600070
Editora
European Centre for Disease Prevention and Control