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Seroprevalence to cytomegalovirus in the Portuguese population, 2002-2003

dc.contributor.authorLopo, Sílvia
dc.contributor.authorVinagre, Elsa
dc.contributor.authorPalminha, Paula
dc.contributor.authorPaixão, Maria Teresa
dc.contributor.authorNogueira, Paulo
dc.contributor.authorFreitas, Maria Graça
dc.date.accessioned2012-02-27T11:59:57Z
dc.date.available2012-02-27T11:59:57Z
dc.date.issued2011-06-23
dc.description.abstractThe prevalence of cytomegalovirus (CMV) infections ranges between 50% and 85% in adults in the United States, and its epidemiology varies in different regions of the world and between socioeconomic and age groups. In Portugal, no study has been carried out to date to determine the prevalence of CMV in the general population. Under the second National Serological Survey conducted in continental Portugal in 2001–2002, we estimated the prevalence of individuals with antibodies to CMV using indirect immunofluorescence to detect virus-specific IgG. The population sample included 2,143 individuals of both sexes and different ages from all 18 districts in Portugal. The national seroprevalence of CMV was determined as 77%. We analysed the proportion of CMV IgG by sex, age group and district of residence. This was the first nationally representative study of seroprevalence of CMV in Portugal. The results of the study indicate that CMV infection is highly prevalent in the population and occurs mainly in the first years of life.por
dc.description.sponsorshipThe project ‘Evaluation of National Vaccination Programme and improving their cost-effectiveness’ is responsibility of the Directorate General of Health and was funded by Health XXI Programme, under the III Community Support Framework. The planning of the protocol, the fieldwork and analysis of data were done by technicians of the National Observatory of Health (currently the Department of Epidemiology) in the National Institute of Health. Monitoring and review of all phases of the project was the responsibility of a group of experts in the clinical, laboratory and epidemiologic area.por
dc.identifier.citationEuro Surveill. 2011 Jun 23;16(25). pii: 19896por
dc.identifier.issn1560-7917
dc.identifier.urihttp://hdl.handle.net/10400.18/646
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherEuropean Centre for Disease Prevention and Controlpor
dc.relation.publisherversionhttp://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19896por
dc.subjectEpidemiologia Clínicapor
dc.subjectInfecções Sistémicas e Zoonosespor
dc.subjectEstados de Saúde e de Doençapor
dc.subjectSeroprevalênciapor
dc.subjectSeroprevalencepor
dc.subjectCytomegaloviruspor
dc.subjectPortugalpor
dc.subjectPortuguese Populationpor
dc.titleSeroprevalence to cytomegalovirus in the Portuguese population, 2002-2003por
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage6por
oaire.citation.startPage1por
oaire.citation.titleEurosurveillancepor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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