Differential gene expression in cells from Fabry and Gaucher diseases:
cell reprogramming and culture aging

Amaral, Olga; Santos, Renato; Ribeiro, Diogo

Publication

Differential gene expression in cells from Fabry and Gaucher diseases: cell reprogramming and culture aging

2020-04Conference object

dc.contributor.author	Amaral, Olga
dc.contributor.author	Santos, Renato
dc.contributor.author	Ribeiro, Diogo
dc.date.accessioned	2020-05-25T15:14:48Z
dc.date.available	2020-05-25T15:14:48Z
dc.date.issued	2020-04
dc.description.abstract	Gene expression varies deeply, even in the same individual’s cells, depending on stress factors, cell aging, gene variants or gene and cell manipulation In this work, gene expression can be seen to shift in many genes, using fibroblasts from donors with Fabry and Gaucher type 3 genetic diseases Tests were also made to compare the impact of aging cultures Real time qRT PCR protocols for genes of interest were used for expression comparison after cell induction and reprogramming.	pt_PT
dc.description.sponsorship	FCT project PTDC/BIM-MEC/4762/2014 (CeMoLy)	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.uri	http://hdl.handle.net/10400.18/6798
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by-nc/4.0/	pt_PT
dc.subject	Gene Expression	pt_PT
dc.subject	iPSCs	pt_PT
dc.subject	RNA	pt_PT
dc.subject	Cell Models	pt_PT
dc.subject	Lysosomal Disorders	pt_PT
dc.subject	Fabry Disease	pt_PT
dc.subject	Gaucher disease	pt_PT
dc.subject	Doenças Genéticas
dc.subject	Genética Humana
dc.title	Differential gene expression in cells from Fabry and Gaucher diseases: cell reprogramming and culture aging	pt_PT
dc.type	conference object
dspace.entity.type	Publication
oaire.citation.conferencePlace	Yorba Linda, California	pt_PT
oaire.citation.title	8th Annual Genetics Virtual Week, Labroots, 21-23 april 2020	pt_PT
rcaap.rights	openAccess	pt_PT
rcaap.type	conferenceObject	pt_PT