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2015/16 seasonal vaccine effectiveness against hospitalisation with influenza A(H1N1)pdm09 and B among elderly people in Europe: results from the I-MOVE+ project

2017-07-30Journal article Open access
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dc.contributor.authorRondy, Marc
dc.contributor.authorLarrauri, Amparo
dc.contributor.authorCasado, Itziar
dc.contributor.authorAlfonsi, Valeria
dc.contributor.authorPitigoi, Daniela
dc.contributor.authorLaunay, Odile
dc.contributor.authorSyrjänen, Ritva K
dc.contributor.authorGefenaite, Giedre
dc.contributor.authorMachado, Ausenda
dc.contributor.authorVučina, Vesna Višekruna
dc.contributor.authorHorváth, Judith Krisztina
dc.contributor.authorParadowska-Stankiewicz, Iwona
dc.contributor.authorMarbus, Sierk D
dc.contributor.authorGherasim, Alin
dc.contributor.authorDíaz-González, Jorge Alberto
dc.contributor.authorRizzo, Caterina
dc.contributor.authorIvanciuc, Alina E
dc.contributor.authorGaltier, Florence
dc.contributor.authorIkonen, Niina
dc.contributor.authorMickiene, Aukse
dc.contributor.authorGomez, Veronica
dc.contributor.authorKurečić Filipović, Sanja
dc.contributor.authorFerenczi, Annamária
dc.contributor.authorKorcinska, Monika R
dc.contributor.authorvan Gageldonk-Lafeber, Rianne
dc.contributor.authorI-MOVE+ hospital working group
dc.contributor.authorValenciano, Marta
dc.date.accessioned2018-02-26T16:06:09Z
dc.date.available2018-02-26T16:06:09Z
dc.date.issued2017-07-30
dc.descriptionMembers of the I-MOVE+ project - Portugal: Baltazar Nunes, Ana Paula Rodrigues, Raquel Guiomar (Infectious Diseases Department, National Health Institute Doutor Ricardo Jorge, Lisbon, Portugal), Victor Gomes, Filipa Quaresma, Luis Vale, Teresa Garcia, Teresa Bernardo, Liliana Dias, Paula Fonseca, Helena Amorim, João Rolo, Helena Pacheco, Paula Branquinho, Rita Côrte-Real (Centro Hospitalar de Lisboa Central, Lisbon, Portugal),José Poças, Paula Lopes, Maria João Peres, Rosa Ribeiro, Paula Duarte, Ermelinda Pedroso, Sara Rodrigues, Ana Rita Silvério, Diana Gomes Pedreira, Marta Ferreira Fonseca, (Centro Hospitalar de Setúbal, Setúbal, Portugal).pt_PT
dc.description.abstractWe conducted a multicentre test-negative case-control study in 27 hospitals of 11 European countries to measure 2015/16 influenza vaccine effectiveness (IVE) against hospitalised influenza A(H1N1)pdm09 and B among people aged ≥ 65 years. Patients swabbed within 7 days after onset of symptoms compatible with severe acute respiratory infection were included. Information on demographics, vaccination and underlying conditions was collected. Using logistic regression, we measured IVE adjusted for potential confounders. We included 355 influenza A(H1N1)pdm09 cases, 110 influenza B cases, and 1,274 controls. Adjusted IVE against influenza A(H1N1)pdm09 was 42% (95% confidence interval (CI): 22 to 57). It was 59% (95% CI: 23 to 78), 48% (95% CI: 5 to 71), 43% (95% CI: 8 to 65) and 39% (95% CI: 7 to 60) in patients with diabetes mellitus, cancer, lung and heart disease, respectively. Adjusted IVE against influenza B was 52% (95% CI: 24 to 70). It was 62% (95% CI: 5 to 85), 60% (95% CI: 18 to 80) and 36% (95% CI: -23 to 67) in patients with diabetes mellitus, lung and heart disease, respectively. 2015/16 IVE estimates against hospitalised influenza in elderly people was moderate against influenza A(H1N1)pdm09 and B, including among those with diabetes mellitus, cancer, lung or heart diseases.pt_PT
dc.description.sponsorshipThe I-MOVE+ project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 634446.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationEuro Surveill. 2017 Jul 27;22(30) pii: 30580. doi: 10.2807/1560-7917.ES.2017.22.30.30580pt_PT
dc.identifier.doi10.2807/1560-7917.ES.2017.22.30.30580pt_PT
dc.identifier.issn1025-496X
dc.identifier.urihttp://hdl.handle.net/10400.18/5072
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherEuropean Centre for Disease Prevention and Controlpt_PT
dc.relationI-MOVE+ Integrated Monitoring of Vaccines Effects in Europe: a platform to measure and compare effectiveness and impact of influenza and pneumococcal vaccines and vaccination strategies in the elderly
dc.relation.publisherversionhttp://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2017.22.30.30580pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCase Controlpt_PT
dc.subjectElderlypt_PT
dc.subjectInfluenzapt_PT
dc.subjectHospitalisationpt_PT
dc.subjectSevere Acute Respiratory Infectionpt_PT
dc.subjectVaccine Effectivenesspt_PT
dc.subjectVaccine-preventable Diseasespt_PT
dc.subjectEfetividade da Vacina Antigripalpt_PT
dc.subjectHospitalpt_PT
dc.subjectVacina Antigripalpt_PT
dc.subjectCuidados de Saúdept_PT
dc.subjectInfecções Respiratórias
dc.title2015/16 seasonal vaccine effectiveness against hospitalisation with influenza A(H1N1)pdm09 and B among elderly people in Europe: results from the I-MOVE+ projectpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleI-MOVE+ Integrated Monitoring of Vaccines Effects in Europe: a platform to measure and compare effectiveness and impact of influenza and pneumococcal vaccines and vaccination strategies in the elderly
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/634446/EU
oaire.citation.issue30pt_PT
oaire.citation.startPage30580pt_PT
oaire.citation.titleEurosurveillancept_PT
oaire.citation.volume22pt_PT
oaire.fundingStreamH2020
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameEuropean Commission
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublicationccfd73a6-6f3c-4702-956c-544973bca97d
relation.isProjectOfPublication.latestForDiscoveryccfd73a6-6f3c-4702-956c-544973bca97d

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