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earlyMYCO project - Early-life exposure to mycotoxins: a neglected issue?

2019-09Conference object Restricted access
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dc.contributor.authorAlvito, Paula
dc.contributor.authorAmador, P.
dc.contributor.authorBroeiro, Paula
dc.contributor.authorCaldeira, T
dc.contributor.authorDe Boevre, Marthe
dc.contributor.authorDe Saeger, Sarah
dc.contributor.authorDuarte, E.
dc.contributor.authorFerreira, M.
dc.contributor.authorLamy, Elisabete
dc.contributor.authorMexia, R.
dc.contributor.authorNamorado, S.
dc.contributor.authorNunes, B.
dc.contributor.authorNunes, C.
dc.contributor.authorPires, S.
dc.contributor.authorSilva, M.J.
dc.contributor.authorSilva, Susana
dc.contributor.authorVidal, A.
dc.contributor.authorMartins, C.
dc.contributor.authorAssunção, R.
dc.date.accessioned2020-05-15T18:23:32Z
dc.date.available2020-05-15T18:23:32Z
dc.date.issued2019-09
dc.description.abstractRecent studies under MYCOMIX project reported that Portuguese children until 3 years old are exposed to multiple mycotoxins through food consumption, constituting a potential health threat. Aflatoxins (carcinogenic toxins) represented the main risk contributors and deoxynivalenol (a non-carcinogenic toxin associated with immunological and gastrointestinal toxic effects) showed the highest daily intake of the studied mycotoxins. These results opened new research perspectives and emphasized the need to accurately assess the prenatal and lactational exposure to mycotoxins in a critical and vulnerable period of life. Early-life exposure of children occurs during gestation through transfer of toxic substances present in the maternal diet to the fetus and later on, during lactation, through the breast milk. Considering this, the national project earlyMYCO – Early-life exposure to MYCOtoxins and its impact on health aims at assessing the risk of early-life exposure to mycotoxins. earlyMYCO proposes to answer several key questions including what extent are pregnant women and infants until six months exposed to mycotoxins in Portugal? Is this exposure a health threat? With this purpose, earlyMYCO gathered a multidisciplinar team with expertise on medical sciences, public health and toxicology to perform i) an epidemiological study, including the recruitment of pregnant women and infants, food survey and biological sample collection and ii) mycotoxin exposure assessment in pregnant women and infants using biomarkers of exposure. The epidemiological study was approved by INSA’s Ethical Committee and will be conducted in the Primary Health Care of Central Lisboa. The biomonitoring study will use advanced analytical methodologies and will provide data to perform the exposure assessment. Due to the increasing prevalence in food commodities, mycotoxins appear to be important, but often neglected contaminants in terms of health impact on human population especially in vulnerable groups as children. It is expected that results obtained within earlyMYCO will contribute to understand the impact of mycotoxin early-life exposure.pt_PT
dc.description.sponsorshipFCT/MCTES through national funds (PTDC/MED-TOX/28762/2017) and co-funded by iMed.ULisboa (Pest-UID/DTP/04138/2018), CESAM (UID/AMB/50017/2019) and MYTOX-SOUTH, Ghent University, BEpt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/6676
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectMicotoxinspt_PT
dc.subjectChildren Exposure Assessmentpt_PT
dc.subjectAvaliação de Riscopt_PT
dc.subjectSaúde Humanapt_PT
dc.subjectSegurança Alimentarpt_PT
dc.subjectToxicologiapt_PT
dc.subjectMYCOMIXpt_PT
dc.subjectPortugalpt_PT
dc.titleearlyMYCO project - Early-life exposure to mycotoxins: a neglected issue?pt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FDTP%2F04138%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAMB%2F50017%2F2013/PT
oaire.citation.conferencePlaceAveiro, Portugalpt_PT
oaire.citation.title3rd International Conference on Food Contaminants: Challenges on Risk Assessment, 26-27 September 2019pt_PT
oaire.fundingStream5876
oaire.fundingStream5876
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isProjectOfPublication8b7dc2e1-c04d-4a11-8fa9-83ead9d8f256
relation.isProjectOfPublication1d7db62a-6440-4ccb-a5cc-c3f76c8585b3
relation.isProjectOfPublication.latestForDiscovery8b7dc2e1-c04d-4a11-8fa9-83ead9d8f256

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