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Analytical techniques for multiplex analysis of protein biomarkers

2020-04Journal article Open access
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dc.contributor.authorVan Gool, Alain
dc.contributor.authorCorrales, Fernado
dc.contributor.authorČolović, Mirjana
dc.contributor.authorKrstić, Danijela
dc.contributor.authorOliver-Martos, Begona
dc.contributor.authorMartínez-Cáceres, Eva
dc.contributor.authorJakasa, Ivone
dc.contributor.authorGajski, Goran
dc.contributor.authorBrun, Virginie
dc.contributor.authorKyriacou, Kyriacos
dc.contributor.authorBurzynska-Pedziwiatr, Izabela
dc.contributor.authorWozniak, Lucyna Alicja
dc.contributor.authorNierkens, Stephan
dc.contributor.authorPascual García, César
dc.contributor.authorKatrlik, Jaroslav
dc.contributor.authorBojic-Trbojevic, Zanka
dc.contributor.authorVacek, Jan
dc.contributor.authorLlorente, Alicia
dc.contributor.authorAntohe, Felicia
dc.contributor.authorSuica, Viorel
dc.contributor.authorSuarez, Guillaume
dc.contributor.authort’Kindt, Ruben
dc.contributor.authorMartin, Petra
dc.contributor.authorPenque, Deborah
dc.contributor.authorMartins, Ines Lanca
dc.contributor.authorBodoki, Ede
dc.contributor.authorIacob, Bogdan-Cezar
dc.contributor.authorAydindogan, Eda
dc.contributor.authorTimur, Suna
dc.contributor.authorAllinson, John
dc.contributor.authorSutton, Christopher
dc.contributor.authorLuider, Theo
dc.contributor.authorWittfooth, Saara
dc.contributor.authorSammar, Marei
dc.date.accessioned2021-04-07T17:41:56Z
dc.date.available2021-04-07T17:41:56Z
dc.date.issued2020-04
dc.description.abstractThe importance of biomarkers for pharmaceutical drug development and clinical diagnostics is more significant than ever in the current shift toward personalized medicine. Biomarkers have taken a central position either as companion markers to support drug development and patient selection, or as indicators aiming to detect the earliest perturbations indicative of disease, minimizing therapeutic intervention or even enabling disease reversal. Protein biomarkers are of particular interest given their central role in biochemical pathways. Hence, capabilities to analyze multiple protein biomarkers in one assay are highly interesting for biomedical research.pt_PT
dc.description.sponsorshipThis paper was funded by the European cooperation in science and technology - COST action No. CA16113 - CliniMARK: ‘good biomarker practice’ to increase the number of clinically validated biomarkers.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationExpert Rev Proteomics. 2020 Apr;17(4):257-273. doi: 10.1080/14789450.2020.1763174. Epub 2020 May 19.pt_PT
dc.identifier.doi10.1080/14789450.2020.1763174pt_PT
dc.identifier.issn1478-9450
dc.identifier.urihttp://hdl.handle.net/10400.18/7662
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor and Francis/ Expert Reviewspt_PT
dc.relation.publisherversionhttps://www.tandfonline.com/doi/full/10.1080/14789450.2020.1763174pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectMultiplexingpt_PT
dc.subjectMass Spectrometrypt_PT
dc.subjectValidationpt_PT
dc.subjectBiomarkerspt_PT
dc.subjectGenómica Funcional e Estruturalpt_PT
dc.titleAnalytical techniques for multiplex analysis of protein biomarkerspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage273pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage257pt_PT
oaire.citation.titleExpert Review of Proteomicspt_PT
oaire.citation.volume17pt_PT
rcaap.embargofctAcesso de acordo com página web do editor da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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