Repository logo
 
Publication

MERSEL FISH: Development and validation of a new analytical approach for the simultaneous speciation analysis of mercury and selenium by HPLC ICP MS

2020-03-18Conference object Restricted access
Simple item page
dc.contributor.authorMendes Ribeiro, Mariana
dc.contributor.authorLeufroy, Axelle
dc.contributor.authorDanion, Morgane
dc.contributor.authorCastanheira, Isabel
dc.contributor.authorSilva, José Armando
dc.contributor.authorJitaru, Petru
dc.date.accessioned2021-03-10T14:56:22Z
dc.date.available2021-03-10T14:56:22Z
dc.date.issued2020-03-18
dc.description.abstractMercury (Hg) is one of the most hazardous chemicals to the environment and the most worrisome contaminant for public health. This is due to its extreme toxicity, particularly in the methylated form which is biomagnified in the food chain, the main pathway of contamination of the humans. The great ability of CH3Hg+ to be bioaccumulated in the aquatic food chain leads to considerably elevated levels of Hg in aquatic organisms, despite nearly immeasurable quantities in the water column. No maximum level for CH3Hg+ is yet regulated by the European commission (EC) in fishery products, despite its extreme toxicity. This is most likely arising from the difficulty in performing accurate speciation analysis of CH3Hg+ in complex matrices such as fishery products. It is also interesting to note that mercury bio-availability seems to be linked to the selenium levels. Although it was shown for a few decades that selenium (Se) shows protective effects against Hg bioaccumulation and toxicity, the mechanism is very poorly understood nowadays. This work report the development and optimization of a new analytical approach for the simultaneous speciation analysis of mercury (Hg2+ and CH3Hg+) and selenium (SeIV, Se VI, SeMet and SeCys) in fish by HPLC-ICP-MS. This method will be employed further for the assessment of dietary exposure to Hg & Se species bio-accumulation by fish, for the analysis of cooked samples as well as for the in vitro simulated digestion studies, to achieve the main aim of this study which is a deep assessment of the Hg-Se interaction in fish and the human dietary exposure.pt_PT
dc.description.sponsorshipEste trabalho foi desenvolvido com o apoio da FCT.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/7403
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectMercurypt_PT
dc.subjectSeleniumpt_PT
dc.subjectSimultaneous Speciation Analysispt_PT
dc.subjectHPLC ICP MSpt_PT
dc.subjectComposição dos Alimentospt_PT
dc.titleMERSEL FISH: Development and validation of a new analytical approach for the simultaneous speciation analysis of mercury and selenium by HPLC ICP MSpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceParis, Fançapt_PT
oaire.citation.titleANSES's Scientific and Doctoral Days, French Agency for Food, Environmental and Occupational Health & Safety, 18-19 March 2020pt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Mariana Ribeiro_20 03 18_JSDA Poster.pdf
Size:
929.56 KB
Format:
Adobe Portable Document Format
Download

Collections

DAN - Posters/abstracts em congressos internacionais