Constructing a cardiac cell model from a patient with Fabry disease

Duarte, Ana Joana; Ribeiro, Diogo; Amaral, Olga

http://hdl.handle.net/10400.18/8122

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Authors

Duarte, Ana Joana

Ribeiro, Diogo

Amaral, Olga

Abstract(s)

• We successfully achieve an iPSC line from a patient with Fabry Disease • Our line has the characteristics of stem cells and has the hability to differentiate into the 3 germ layers • After induction with specific cardiac effectors we achieved beating iPSC-CMs