Emergence of  ST131 carrying carbapenemase genes, European Union/European Economic Area, August 2012 to May 2024

Analysis of 594 isolates of sequence type (ST)131 and its single locus variants carrying carbapenemase genes from 17 European Union/European Economic Area countries revealed acquisition of 18 carbapenemase variants, mainly in ST131 clades A and C. Most frequent were (n = 230) and (n = 224), detected in 14 and 12 countries, respectively. Isolates carrying have increased rapidly since 2021. The increasing detection of carbapenemase genes in the high-risk lineage ST131 is a public health concern.

Keywords

Carbapenem-resistant Enterobacterales Escherichia coli Antibiotics Antimicrobial Resistance Carbapenemase Cross-border Spread Surveillance Whole Genome Sequencing Resistência aos Antimicrobianos