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Lipoprotein(a) levels and LPA genotype in patients with Familial Hypercholesterolemia

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dc.contributor.authorMedeiros, A.M.
dc.contributor.authorAlves, A.C.
dc.contributor.authorBourbon, M.
dc.date.accessioned2020-05-26T07:04:52Z
dc.date.available2020-05-26T07:04:52Z
dc.date.issued2019-10
dc.description.abstractFamilial Hypercholesterolemia (FH) patients have na increased cardiovascular risk due to high TC or LDL-C levels. Lp(a) chemical structure is similar to LDL and elevated Lp(a) is considered an independent risk factor for cardiovascular disease (CVD). Recently, it has been described that in patients with high Lp(a), the Lp(a)-C can contribute up to 25% to 50% of all LDL-C. Two LPA variants (rs3798220 and rs10455872) were strongly associated with high Lp(a) levels and increased risk of CVD. In the present work we aim to determine how elevated Lp(a) concentrations and LPA genotype may contribute to clinical phenotype of FH.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/6805
dc.language.isoengpt_PT
dc.publisherInstituto Nacional de Saúde Doutor Ricardo Jorge, IPpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectFamilial Hypercholesterolemiapt_PT
dc.subjectCardiovascular Diseasespt_PT
dc.subjectDoenças Cardio e Cérebro-vascularespt_PT
dc.titleLipoprotein(a) levels and LPA genotype in patients with Familial Hypercholesterolemiapt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlacePeniche, Portugalpt_PT
oaire.citation.titleXXVII Congresso Português de Aterosclerose, 15-16 novembro 2019pt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typeconferenceObjectpt_PT

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