Relation between triglycerides associated polymorphisms and lipid profile in Familial Combined Hyperlipidaemia

Publication

dc.contributor.author	Santos, T.
dc.contributor.author	Rato, Q.
dc.contributor.author	Gaspar, I.M.
dc.contributor.author	Bourbon, M.
dc.date.accessioned	2012-07-10T12:51:23Z
dc.date.available	2012-07-10T12:51:23Z
dc.date.issued	2012-05
dc.description.abstract	Familial Combined Hyperlipidaemia (FCHL) is a genetic disorder characterized by highly atherogenic profile with prevalence of sdLDL particles, hyperlipidaemia (hypertriglyceridaemia and/or hypercholesterolaemia) and high apoB levels (>120 mg/dL), with different lipid profiles in members of the same family. Some polymorphisms in several genes (LPL -93T>G/D9N, APOAIV Q360H and V13M, APOAV -1131T>C and S19W, APOCIII 3238C>G, USF1s1 and USF1s2) have been associated with higher levels of triglycerides (TG) or FCHL. Hypertriglyceridaemia (HTG) has also been suggested by some authors as an independent risk factor for cardiovascular diseases (CVD).	por
dc.identifier.uri	http://hdl.handle.net/10400.18/901
dc.language.iso	eng	por
dc.publisher	Instituto Nacional de Saúde Doutor Ricardo Jorge, IP	por
dc.subject	Doenças Cardio e Cérebro-vasculares	por
dc.title	Relation between triglycerides associated polymorphisms and lipid profile in Familial Combined Hyperlipidaemia	por
dc.type	conference object
dspace.entity.type	Publication
oaire.citation.conferencePlace	Milan, Italy	por
oaire.citation.title	80th European Atherosclerosis Society Congress-EAS, 25-28 May 2012	por
rcaap.rights	embargoedAccess	por
rcaap.type	conferenceObject	por

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