Sandfly-Borne Phleboviruses in Portugal: Four and Still Counting

Amaro, Fátima; Zé-Zé, Líbia; Alves, Maria João

http://hdl.handle.net/10400.18/8527

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Authors

Amaro, Fátima

Zé-Zé, Líbia

Alves, Maria João

Abstract(s)

According to ICTV, there are currently 66 known phlebovirus species. More than 40 of these viruses were isolated or detected in phlebotomine sandflies and some of them are known pathogens. In Portugal, information about sandfly-borne phleboviruses is scarce and scattered sandfly-borne diseases are neglected and often not considered in differential diagnoses. The main objective of this work was to gather the existing information and to raise awareness about the circulating phleboviruses in this country. To date, Massilia and Alcube phleboviruses have been isolated from sandflies in southern Portugal. Human infections with Toscana and Sicilian phleboviruses have been reported, as well as seroprevalence in cats and dogs. More studies are needed in order to understand if the viruses isolated during the entomological surveys have an impact on human health and to fully understand the real importance of the already recognized pathogens in our country.