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Genetic characterization of Bhanja virus and Palma virus, two tick-borne phleboviruses
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Orientador(es)
Resumo(s)
The genomes of Bhanja virus (BHAV) and Palma virus (PALV) two tick-borne viruses hitherto grouped into the Bhanja virus antigenic complex of the Bunyaviridae were determined by pyrosequencing. Phylogenetic analysis groups all three segments of BHAV and PALV into a distinct clade of tick-borne phleboviruses together with the newly described severe fever with thrombocytopenia syndrome virus and Uukuniemi virus. The terminal signature sequences which are signatures for taxonomic grouping and important for virus replication and RNA transcription show marked differences in the L- and S-segments.
Descrição
Palavras-chave
Infecções Sistémicas e Zoonoses Bhanja virus Palma Virus Unassigned Bunyavirus Phlebovirus 454 Pyrosequencing
Contexto Educativo
Citação
Virus Genes. 2012 Jul 18. [Epub ahead of print]