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Use of quasi-experimental studies to evaluate causal effects of public health interventions in Portugal: a scoping review

2025-11-24Artigo científico Acesso aberto
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datacite.subject.fosCiências Médicas
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorLeite, Andreia
dc.contributor.authorKislaya, Irina
dc.contributor.authorMachado, Ausenda
dc.contributor.authorAguiar, P.
dc.contributor.authorNunes, B.
dc.contributor.authorDias, Carlos Matias
dc.date.accessioned2026-01-09T10:50:59Z
dc.date.available2026-01-09T10:50:59Z
dc.date.issued2025-11-24
dc.description.abstractBackground: Quasi-experimental designs are a valid option to assess causal effects of public health interventions when randomized studies are unfeasible, but not widely used in Portugal. We identified and reviewed characteristics of studies employing quasi-experimental designs to evaluate causal effects of public health interventions in Portugal. Methods: PubMed, Scopus, Web of Science and CINHAL were searched, alongside grey literature, reference mining and contact of authors of eligible studies. We extracted information on the intervention assessed, study design, outcomes assessed, statistical analysis and reporting guidelines. Results: We identified 1143 studies; 25 were eligible. Studies assessed interventions in various areas, mainly healthcare services (28.0%), drugs/tobacco consumption policy (20.0%), and COVID-19 related restrictions (20.0%). Studies employed interrupted time series (56.0%) and difference-in-differences designs (44.0%). Analyses utilised regression-based models, namely linear (48.0%), negative binominal (20.0%) and logistic (12.0%). Studies analysed 53 outcomes, with two outcomes per study on average. No reporting guidelines were mentioned. Conclusions: There is a limited number of studies using quasi-experimental designs to estimate the causal effects of public health interventions in Portugal, mainly interrupted time series and difference-in-differences. Training in this area might promote the adequate use and dissemination of quasi-experimental studies.eng
dc.description.sponsorshipThis research was funded by Fundação para a Ciência e Tecnologia (FCT, Portugal) through national funds to the Associated Laboratory in Translation and Innovation Towards Global Health REAL (LA/P/0117/2020).
dc.identifier.citationBMC Med Res Methodol. 2025 Nov 24;25(1):263. doi: 10.1186/s12874-025-02701-3
dc.identifier.doi10.1186/s12874-025-02701-3
dc.identifier.eissn1471-2288
dc.identifier.pmid41286694
dc.identifier.urihttp://hdl.handle.net/10400.18/10668
dc.language.isoeng
dc.peerreviewedyes
dc.publisherBioMed Central
dc.relationTranslation and Innovation towards Global Health
dc.relation.hasversionhttps://link.springer.com/article/10.1186/s12874-025-02701-3
dc.relation.ispartofBMC Medical Research Methodology
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectCausal Effects
dc.subjectPublic Health
dc.subjectQuasi-Experimental Studies
dc.subjectDeterminantes da Saúde e da Doença
dc.subjectInvestigação em Políticas de Saúde
dc.subjectPortugal
dc.titleUse of quasi-experimental studies to evaluate causal effects of public health interventions in Portugal: a scoping revieweng
dc.typejournal article
dcterms.referenceshttps://static-content.springer.com/esm/art%3A10.1186%2Fs12874-025-02701-3/MediaObjects/12874_2025_2701_MOESM1_ESM.docx
dspace.entity.typePublication
oaire.awardTitleTranslation and Innovation towards Global Health
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0117%2F2020/PT
oaire.citation.issue1
oaire.citation.startPage263
oaire.citation.titleBMC Medical Research Methodology
oaire.citation.volume25
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isProjectOfPublication8fda9aa0-466f-48d1-8017-ebb8180fc3ae
relation.isProjectOfPublication.latestForDiscovery8fda9aa0-466f-48d1-8017-ebb8180fc3ae

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