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Draft Genomic Analysis of an Avian Multidrug Resistant Morganella morganii Isolate Carrying qnrD1

dc.contributor.authorJones-Dias, Daniela
dc.contributor.authorClemente, Lurdes
dc.contributor.authorMoura, Inês B
dc.contributor.authorSampaio, Daniel A
dc.contributor.authorAlbuquerque, Teresa
dc.contributor.authorVieira, Luís
dc.contributor.authorManageiro, Vera
dc.contributor.authorCaniça, Manuela
dc.date.accessioned2017-02-17T11:49:34Z
dc.date.available2017-02-17T11:49:34Z
dc.date.issued2016-10-25
dc.description.abstractMorganella morganii is a commensal bacterium and opportunistic pathogen often present in the gut of humans and animals. We report the 4.3 Mbp draft genome sequence of a M. morganii isolated in association with an Escherichia coli from broilers in Portugal that showed macroscopic lesions consistent with colisepticemia. The analysis of the genome matched the multidrug resistance phenotype and enabled the identification of several clinically important and potentially mobile acquired antibiotic resistance genes, including the plasmid-mediated quinolone resistance determinant qnrD1. Mobile genetic elements, prophages, and pathogenicity factors were also detected, improving our understanding toward this human and animal opportunistic pathogen.pt_PT
dc.description.sponsorshipDJ-D has received research funding from Fundação para a Ciência e a Tecnologia (FCT, grant number SFRH/BD/80001/2011). VM was supported by FCT fellowship (grant SFRH/BPD/77486/2011), financed by the European Social Funds (COMPETE-FEDER) and national funds of the Portuguese Ministry of Education and Science (POPHQREN). We thank the support of FCT grant number PEstOE/AGR/UI0211/2011-2014 and UID/MULTI/00211/2013.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFront Microbiol. 2016 Oct 25;7:1660. eCollection 2016. doi:10.3389/fmicb.2016.01660pt_PT
dc.identifier.doi10.3389/fmicb.2016.01660pt_PT
dc.identifier.issn1664-302X
dc.identifier.urihttp://hdl.handle.net/10400.18/4249
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherFrontiers Mediapt_PT
dc.relation.publisherversionhttp://journal.frontiersin.org/article/10.3389/fmicb.2016.01660/fullpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectqnrD1pt_PT
dc.subjectPlasmidpt_PT
dc.subjectMultidrug Resistancept_PT
dc.subjectMorganella Morganiipt_PT
dc.subjectWGSpt_PT
dc.subjectResistência aos Antimicrobianospt_PT
dc.titleDraft Genomic Analysis of an Avian Multidrug Resistant Morganella morganii Isolate Carrying qnrD1pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/PEst-OE%2FAGR%2FUI0211%2F2014/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F00211%2F2013/PT
oaire.citation.startPage1660pt_PT
oaire.citation.titleFrontiers in Microbiologypt_PT
oaire.citation.volume7pt_PT
oaire.fundingStream5876
oaire.fundingStream5876
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublicationd3e4188b-642e-4ad7-9a4d-aeea65a89449
relation.isProjectOfPublication4641127c-7dd5-44f4-a3d1-d3c4d744ba51
relation.isProjectOfPublication.latestForDiscovery4641127c-7dd5-44f4-a3d1-d3c4d744ba51

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