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Flavouring Group Evaluation 87, Revision 3 (FGE.87Rev3): Consideration of bicyclic secondary alcohols, ketones and related esters evaluated by JECFA (63rd meeting) structurally related to bicyclic secondary alcohols, ketones and related esters evaluated in FGE.47Rev1

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dc.contributor.authorEFSA Panel on Food Additives and Flavourings (FAF)
dc.contributor.authorCastle, Laurence
dc.contributor.authorAndreassen, Monica
dc.contributor.authorAquilina, Gabriele
dc.contributor.authorBastos, Maria
dc.contributor.authorBoon, Polly
dc.contributor.authorFallico, Biagio
dc.contributor.authorFitzGerald, Rex
dc.contributor.authorFrutos Fernández, María José
dc.contributor.authorGrasl‐Kraupp, Bettina
dc.contributor.authorGundert‐Remy, Ursula
dc.contributor.authorGürtler, Rainer
dc.contributor.authorHoudeau, Eric
dc.contributor.authorKurek, Marcin
dc.contributor.authorLouro, Henriqueta
dc.contributor.authorMorales, Patricia
dc.contributor.authorPassamonti, Sabina
dc.contributor.authorBenigni, Romualdo
dc.contributor.authorDegen, Gisela
dc.contributor.authorEngel, Karl‐Heinz
dc.contributor.authorCarfí, Maria
dc.contributor.authorMartino, Carla
dc.date.accessioned2026-10-07T10:11:03Z
dc.date.available2026-10-07T10:11:03Z
dc.date.issued2026-01-22
dc.descriptionEFSA Panel on Food Additives and Flavourings (FAF) Panel Members: Henriqueta Louro (INSA).
dc.description.abstractThe Panel on Food Additives and Flavourings (FAF) of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) and to decide whether further evaluation is necessary, as laid down in Commission Regulation (EC) No. 1565/2000. The present consideration concerns a group of 19 bicyclic secondary alcohols, ketones and related esters evaluated by JECFA at the 63rd meeting. This revision of FGE.87 is made due to new information on annual production volume, allowing the calculation of maximised survey‐derived daily intake (MSDI) for 4,4a,5,6‐tetrahydro‐7‐methylnaphthalen‐2(3H)‐one [FL‐no: 07.136]. In addition, new data on uses and use levels for the substances [FL‐no: 07.089, 07.0136, 07.153 and 07.159] have been provided and considered for the estimation of exposure (mTAMDI approach). For [FL‐no: 07.136], the Panel agrees with the Procedure as applied by JECFA and with JECFA conclusion: ‘No safety concern at estimated levels of intake as flavouring substance’, when based on the MSDI approach. For the other 18 substances considered in FGE.87Rev3, the same conclusion was already drawn in FGE.87Rev2. For [FL‐no: 07.136], the mTAMDI exposure estimate is below the TTC for structural class II substances. Accordingly, no further data are required in the context of the current evaluation programme. For [FL‐no: 07.089, 07.153, 07.159], mTAMDI exposure estimates are above the TTC for structural class II substances; therefore, more reliable data on uses and use levels should be provided in order to refine the exposure assessment and to finalise their safety evaluation. For the remaining 15 substances, use levels are needed to calculate the mTAMDIs in order to identify those flavouring substances that need more refined exposure assessments and to finalise the evaluation. Information on specifications for the materials of commerce is considered adequate for all 19 substances.eng
dc.identifier.citationEFSA J . 2026 Jan 22;24(1):e9853. doi: 10.2903/j.efsa.2026.9853. eCollection 2026 Jan
dc.identifier.doi10.2903/j.efsa.2026.9853
dc.identifier.issn1831-4732
dc.identifier.issn1831-4732
dc.identifier.pmid41583340
dc.identifier.urihttp://hdl.handle.net/10400.18/11382
dc.language.isoeng
dc.peerreviewedno
dc.publisherWiley
dc.relation.hasversionhttps://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2026.9853
dc.relation.ispartofEFSA Journal
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectFGE.47
dc.subjectFGE.87
dc.subjectBicycling Secondary Alcohols
dc.subjectKetones and Related Esters
dc.subjectSafety Evaluation
dc.subjectEnvironmental Genotoxicity
dc.subjectFlavouring
dc.subjectEsters
dc.subjectGenotoxicidade Ambiental
dc.titleFlavouring Group Evaluation 87, Revision 3 (FGE.87Rev3): Consideration of bicyclic secondary alcohols, ketones and related esters evaluated by JECFA (63rd meeting) structurally related to bicyclic secondary alcohols, ketones and related esters evaluated in FGE.47Rev1eng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1
oaire.citation.startPagee9853
oaire.citation.titleEFSA Journal
oaire.citation.volume24
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameLouro
person.givenNameHenriqueta
person.identifier157627
person.identifier.ciencia-id721D-2BB1-7DB1
person.identifier.orcid0000-0001-9744-7332
person.identifier.scopus-author-id6507971479
relation.isAuthorOfPublication2361a951-8b9a-4b90-92d6-f6384003a242
relation.isAuthorOfPublication.latestForDiscovery2361a951-8b9a-4b90-92d6-f6384003a242

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