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Patulin in fruit juices: occurrence, bioaccessibility and risk assessment for the Serbian population

dc.contributor.authorTorović, Ljilja
dc.contributor.authorDimitrov, Nina
dc.contributor.authorLopes, André
dc.contributor.authorMartins, Carla
dc.contributor.authorAlvito, Paula
dc.contributor.authorAssunção, Ricardo
dc.date.accessioned2018-03-06T17:28:15Z
dc.date.available2018-03-06T17:28:15Z
dc.date.issued2018-02
dc.description.abstractThis paper reports the first study of patulin occurrence in fruit juices and risk assessment related to patulin intake by children, adolescents and adults in Serbia. During three consecutive years (2013-2015), 142 fruit (apple or multi-fruit) juices were collected from the market and analysed using HPLC-UV. Patulin was found in 51.4% of juices with 0.7% of the samples in excess of the legal limit of 50 μg kg−1 (mean 4.3 μg kg−1). Apple juices showed significantly higher percentage of contaminated samples (74.0% versus 27.5%), as well as higher mean patulin content (6.4 versus 2.1 μg kg−1) when compared with the multi-fruit ones. Bioaccessibility of patulin in fruit juices was studied using the standardized in vitrodigestion method. A mean of 21.6 % of the initial patulin amount reached the end of the intestinal phase showing a significant reduction of this toxin during the human digestion process. Risk assessment of patulin intake by Serbian children, adolescents and adults, conducted by deterministic and probabilistic approaches and including the bioaccessibility results, revealed no health concern. Although patulin alone does not represent risk, further research should consider its co-occurrence with other toxic substances in food and potential adverse effects of their mixtures.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFood Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 May;35(5):985-995. doi: 10.1080/19440049.2017.1419580. Epub 2018 Feb 21.pt_PT
dc.identifier.doi10.1080/19440049.2017.1419580pt_PT
dc.identifier.issn1944-0049 (print)
dc.identifier.issn1944-0057 (online)
dc.identifier.urihttp://hdl.handle.net/10400.18/5231
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francispt_PT
dc.relation.publisherversionhttps://www.tandfonline.com/doi/full/10.1080/19440049.2017.1419580pt_PT
dc.subjectSegurança Alimentarpt_PT
dc.subjectToxicologiapt_PT
dc.subjectAvaliação de Riscopt_PT
dc.subjectSaúde Humanapt_PT
dc.subjectPatulinpt_PT
dc.subjectBioaccessibilitypt_PT
dc.subjectFruit Juicept_PT
dc.subjectIn vitro Digestionpt_PT
dc.subjectRisk Assessmentpt_PT
dc.titlePatulin in fruit juices: occurrence, bioaccessibility and risk assessment for the Serbian populationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleFood Additives and Contaminants: Part A: Chemistry, Analysis, Control, Exposure and Risk Assessmentpt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT

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