Publication
Contribution to the hazard assessment of benchmark metallic nanomaterials through a set of in vitro genotoxicity assays
| dc.contributor.author | Vital, Nádia | |
| dc.contributor.author | El Yamani, Naouale | |
| dc.contributor.author | Pinhão, Mariana | |
| dc.contributor.author | Rúden-Pra, Elise | |
| dc.contributor.author | Louro, Henriqueta | |
| dc.contributor.author | Dušinská, Maria | |
| dc.contributor.author | Silva, Maria João | |
| dc.date.accessioned | 2019-02-27T11:19:50Z | |
| dc.date.available | 2019-02-27T11:19:50Z | |
| dc.date.issued | 2018-03-19 | |
| dc.description.abstract | Background and Aim: Metall-based nanomaterials (NMs) are among the most commonly applied manufactured nanomaterials (NM). Regardless of the considerable efforts to assess their safety, the presently available data do not allow for general and consistent conclusions. Moreover, the validity of the classical in vitro testing systems for NMs hazard assessment has been questioned and needs confirmation. The present study aimed at evaluating the toxicity of three benchmark metallic NMs - titanium dioxide (NM-100),cerium dioxide (NM-212) and nanosilver - with different physicochemical properties, using a battery of in vitro genotoxicity assays, in an attempt to characterize their toxicity profile. | pt_PT |
| dc.description.sponsorship | This research was partially supported by funding through UID/BIM/00009/2013 (Centre for Toxicogenomics and Human Health, ToxOmics), Fundação para a Ciência e Tecnologia, Portugal, by the FP7 Project NANoREG (GA 310584) and by INSA (2013DGH860). | pt_PT |
| dc.description.version | N/A | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.18/5963 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.relation | A common European approach to the regulatory testing of nanomaterials | |
| dc.relation | A pan-European infrastructure for quality in nanomaterials safety testing | |
| dc.subject | Metallic Nanomaterials | pt_PT |
| dc.subject | Genotoxicity Tests | pt_PT |
| dc.subject | V79 Cells | pt_PT |
| dc.subject | Genotoxicidade Ambiental | pt_PT |
| dc.title | Contribution to the hazard assessment of benchmark metallic nanomaterials through a set of in vitro genotoxicity assays | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | A common European approach to the regulatory testing of nanomaterials | |
| oaire.awardTitle | A pan-European infrastructure for quality in nanomaterials safety testing | |
| oaire.awardURI | info:eu-repo/grantAgreement/EC/FP7/310584/EU | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/UID%2FBIM%2F00009%2F2013/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/EC/FP7/262163/EU | |
| oaire.citation.conferencePlace | Potsdam, Germany | pt_PT |
| oaire.citation.title | 46th EEMGS (European Environmental Mutagenesis and Genomics Society)/30th GUM (Gesellschaft für Umwelt-Mutationsforschung) meeting, 18-21 Mars 2018 | pt_PT |
| oaire.fundingStream | FP7 | |
| oaire.fundingStream | 5876 | |
| oaire.fundingStream | FP7 | |
| person.familyName | Louro | |
| person.givenName | Henriqueta | |
| person.identifier | 157627 | |
| person.identifier.ciencia-id | 721D-2BB1-7DB1 | |
| person.identifier.orcid | 0000-0001-9744-7332 | |
| person.identifier.scopus-author-id | 6507971479 | |
| project.funder.identifier | http://doi.org/10.13039/501100008530 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100008530 | |
| project.funder.name | European Commission | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | European Commission | |
| rcaap.rights | restrictedAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
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