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Risk factors for human papillomavirus infection among women in Portugal: The CLEOPATRE Portugal Study
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Orientador(es)
Resumo(s)
Objective: To investigate demographic, socioeconomic, lifestyle, and medical factors that might predispose
women to cervical human papillomavirus (HPV) infection. Method: A cross-sectional population-based
study was performed. Women aged 18–64 years who attended selected obstetrics and gynecology or sexually
transmitted disease (STD) clinics in mainland Portugal between February 2008 and March 2009 were
recruited, according to an age-stratified sampling strategy. Liquid-based cytology samples were analyzed
centrally for HPV genotype and for cytologic features. Univariate and multivariate logistic regression analyses
identified risk factors for HPV infection. Results: Among the 2326 women evaluated, the crude prevalence of
HPV infection was 19.4%. Lifetime number of sexual partners was a strong predictor of HPV infection (odds
ratio 5.44 for 5–10 partners versus 1 partner; Pb0.001). Other risk factors were young age (particularly
among women aged 20–24 years; Pb0.001); country of birth other than mainland Portugal (P=0.002);
education up to secondary school level (P=0.010); smoking history (≤10 years; P=0.004); and any STD
in the past 12 months (P=0.052). Conclusion: Data from the present study may aid identification of
women at increased risk of HPV infection and target prevention strategies.
Descrição
Palavras-chave
Human Papillomavirus Cervical Infection Portugal Prevalence Risk Factor Infecções Sexualmente Transmissíveis
Contexto Educativo
Citação
Int J Gynaecol Obstet. 2012 Aug;118(2):112-6. Epub 2012 May 16
Editora
Elsevier/ International Federation of Gynecology and Obstetrics (FIGO