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SCCS Opinion on Biphenyl-2-ol and Sodium 2-biphenylolate used in cosmetic products (CAS/EC No. 90-43-7/201-993-5 and 132-27-4/205-055-6)– SCCS/1669/24

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Resumo(s)

Highlights: -o-Phenylphenol (OPP) is safe when used as preservative up to a maximum concentration of 0.2 % in rinse-off cosmetic products; - o-Phenylphenol (OPP) is safe when used as preservative up to a maximum concentration of 0.15 % in leave-on cosmetic products; - Sodium o-Phenylphenate is safe when used as preservative up to a maximum concentration of 0.2 % in rinse-off cosmetic products; - Sodium o-Phenylphenate is safe when used as preservative up to a maximum concentration of 0.15 % in leave-on cosmetic products; - OPP and Sodium o-Phenylphenate, when used together, should not exceed the maximum concentration 0.15 % in leave-on cosmetic products; - OPP and Sodium o-Phenylphenate, when used together, should not exceed the maximum concentration 0.2 % in rinse-off cosmetic products; - Since this safety dossier related to dermally applied products only, the SCCS did not consider oral and inhalation routes; - This assessment did not cover the safety of O-Phenylphenol and Sodium o-Phenylphenate for the environment.

Descrição

Correction: NAM Journal. 2025 Oct 14: 100059. doi:10.1016/j.namjnl.2025.100059

Palavras-chave

o-Phenylphenol (OPP) Safety Assessment Environmental Genotoxicity Cosmetic Ingredients Genotoxicidade Ambiental

Contexto Educativo

Citação

NAM Journal. 2025;1:100035. doi: 10.1016/j.namjnl.2025.100035. Correction: NAM Journal. 2025 Oct 14: 100059. doi:10.1016/j.namjnl.2025.100059

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