Variants within the nitric oxide synthase 1 gene are associated with stroke susceptibility

Manso, H.; Krug, T.; Sobral, J.; Albergaria, I.; Gaspar, G.; Ferro, J.M.; Oliveira, S.A.; Vicente, A.M.

http://hdl.handle.net/10400.18/360

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Resumo(s)

Animal studies have allowed important insights into the role of the nitric oxide synthase (NOS) enzymes in atherosclerosis and hypertension, as well as in stroke. In this study we tested the hypothesis that the NOS1 and NOS3 genes, respectively encoding neuronal NOS (nNOS) and endothelial NOS (eNOS), influence stroke susceptibility and outcome after a stroke event.

Palavras-chave

Genetics Nitric oxide Stroke Susceptibility Doenças Cardio e Cérebro-vasculares

URI

http://hdl.handle.net/10400.18/360

Citação

Atherosclerosis. 2012 Feb;220(2):443-8. doi: 10.1016/j.atherosclerosis.2011.11.011. Epub 2011 Nov 19

Editora

Elsevier

Coleções

DPSPDNT - Artigos em revistas internacionais

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