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Current perspectives of emerging antibiotic resistance in foodborne bacteria

dc.contributor.authorCaniça, Manuela
dc.date.accessioned2017-02-17T13:55:16Z
dc.date.available2017-02-17T13:55:16Z
dc.date.issued2014-09
dc.description.abstractThe increasing occurrence of antibiotic resistance in primary and processed food products, it is of the greatest importance, where the horizontal gene transfer of antibiotic resistance determinants is of huge concern. Indeed, common inhabitants of the human and animal gut of food animals may be disseminated through the food chain. The widespread use of drugs in veterinary can also contribute to the selection of antibiotic resistance mechanisms in pathogenic and non-pathogenic isolates. The common mode of plasmid-mediated resistance (one gene for one class of antimicrobials) requires that an organism harbor and express an array of genes in order to maintain multidrug-resistance; however, for example, at fluoroquinolone resistance, bacteria have an innovation that is a pleiotropic drug-modifying enzyme providing resistance to two structurally and functionally different classes of antibiotics by acquisition of a single gene. But other resources are available to the bacterium confronted with the challenge of antibiotics that is the ability to acquire resistance genes, but not express them; such “nonexpressing” bacteria would remain sensitive to the antibiotic while carrying a potentially transmissible resistance gene. Biofilm formation is also an important phenomenon in the food process. A new dimension in microbial adaptability is taking serious proportions, thus the Council Recommendation “on the prudent use of antimicrobials agents in human medicine” (2002/77/EC), highlight that the “coordination between human, veterinary and environment sectors should be ensured and the magnitude of the relationship between the occurrence of antimicrobial resistant pathogens in humans, animals and the environment should be further clarified”. In fact, a “One Health” approach is being encouraged.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/4255
dc.language.isoporpt_PT
dc.peerreviewednopt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectAntibiotic resistancept_PT
dc.subjectFoodborne pathogenspt_PT
dc.subjectfood chainpt_PT
dc.subjectFood animalspt_PT
dc.subjectHorizontal transferpt_PT
dc.subjectResistência aos Antimicrobianospt_PT
dc.subjectResistência aos Antibióticospt_PT
dc.titleCurrent perspectives of emerging antibiotic resistance in foodborne bacteriapt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceLisboa, Portugalpt_PT
oaire.citation.titleTEMPH 2014 - Trends in Enviromental Microbiology for Public Health, 18-21 September 2014pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT

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