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The first harmonised total diet study in Portugal: Arsenic, cadmium and lead exposure assessment

2025-01-23Artigo científico Acesso aberto
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datacite.subject.fosCiências Agrárias::Biotecnologia Agrária e Alimentar
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorVasco, Elsa
dc.contributor.authorDias, Maria da Graça
dc.contributor.authorOliveira, Luísa
dc.date.accessioned2026-01-28T12:54:00Z
dc.date.available2026-01-28T12:54:00Z
dc.date.issued2025-01-23
dc.description.abstractThe aim of this study was to estimate the 18-74 years old Portuguese population's baseline exposure to inorganic arsenic, cadmium and lead and the risk of exceeding the respective Health Based Guidance Value, using a harmonised Total Diet Study (TDS) methodology. TDS food samples representative of the whole diet were prepared as consumed and analysed for total arsenic, cadmium and lead. European Food Safety Authority's conservative approach was used to estimate inorganic arsenic. Exposure was assessed using the Monte Carlo Risk Assessment software. At upper bound approach, the mean baseline exposure was estimated at 0.28 and 0.35 μg kg body weight day for inorganic arsenic and lead, respectively, and 1.36 μg kg body weight week for cadmium. Margins of exposure of below or close to one were found for inorganic arsenic and lead, whereas 5.4 % of individuals exceeded the Tolerable Weekly Intake for cadmium. These results indicate that adverse health effects cannot be ruled out. Bread was the common main contributor for the exposure to all three elements.eng
dc.description.abstractHighlights: -Portuguese population's mean baselines exposure to iAs, Cd and Pb were assessed. -Mean exposures to iAs and Pb were estimated at 0.28 and 0.35 μg kg−1 bw/day. -Estimated mean exposure to Cd was 1.35 μg kg−1 bw/week. -Potential adverse health effects from exposure to iAs, Cd and Pb cannot be excluded. -Bread was the common main contributor to iAs, Cd and Pb exposure.eng
dc.description.sponsorshipThis research was partially funded by the European Commission’s Seventh Framework Programme [FP7/2012–2016] as a part of TDSExposure project [grant agreement number 289108].
dc.identifier.citationChemosphere. 2025 Mar:372:144003. doi: 10.1016/j.chemosphere.2024.144003. Epub 2025 Jan 23
dc.identifier.doi10.1016/j.chemosphere.2024.144003
dc.identifier.eissn1879-1298
dc.identifier.issn0045-6535
dc.identifier.pmid39716602
dc.identifier.urihttp://hdl.handle.net/10400.18/10774
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.relationTotal Diet Study Exposure
dc.relation.hasversionhttps://www.sciencedirect.com/science/article/pii/S0045653524029114?via%3Dihub
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectContaminants
dc.subjectFood
dc.subjectFoodEx2 Classification System
dc.subjectICP-MS
dc.subjectMonte Carlo Risk Assessment
dc.subjectWhole Diet
dc.subjectComposição dos Alimentos
dc.subjectPortugal
dc.titleThe first harmonised total diet study in Portugal: Arsenic, cadmium and lead exposure assessmenteng
dc.typejournal article
dcterms.referenceshttps://ars.els-cdn.com/content/image/1-s2.0-S0045653524029114-mmc1.docx
dspace.entity.typePublication
oaire.awardTitleTotal Diet Study Exposure
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/289108/EU
oaire.citation.startPage144003
oaire.citation.titleChemosphere
oaire.citation.volume372
oaire.fundingStreamFP7
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameEuropean Commission
relation.isProjectOfPublicationcc652884-f79a-4fc2-8134-0cff92709d45
relation.isProjectOfPublication.latestForDiscoverycc652884-f79a-4fc2-8134-0cff92709d45

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