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Epidemiology of autism spectrum disorder in Portugal: prevalence, clinical characterization, and medical conditions

2007-10Journal article Open access
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dc.contributor.authorOliveira, G.
dc.contributor.authorAtaíde, A.
dc.contributor.authorMarques, C.
dc.contributor.authorMiguel, T.S.
dc.contributor.authorCoutinho, A.M.
dc.contributor.authorMota-Vieira, L.
dc.contributor.authorGonçalves, E.
dc.contributor.authorLopes, N.M.
dc.contributor.authorRodrigues, V.
dc.contributor.authorCarmona da Mota, H.
dc.contributor.authorVicente, A.M.
dc.date.accessioned2011-11-30T17:12:01Z
dc.date.available2011-11-30T17:12:01Z
dc.date.issued2007-10
dc.description.abstractThe objective of this study was to estimate the prevalence of autistic spectrum disorder (ASD) and identify its clinical characterization, and medical conditions in a paediatric population in Portugal. A school survey was conducted in elementary schools, targeting 332,808 school-aged children in the mainland and 10,910 in the Azores islands. Referred children were directly assessed using the Diagnostic and Statistical Manual of Mental Disorders (4th edn), the Autism Diagnostic Interview-Revised, and the Childhood Autism Rating Scale. Clinical history and a laboratory investigation was performed. In parallel, a systematic multi-source search of children known to have autism was carried out in a restricted region. The global prevalence of ASD per 10,000 was 9.2 in mainland, and 15.6 in the Azores, with intriguing regional differences. A diversity of associated medical conditions was documented in 20%, with an unexpectedly high rate of mitochondrial respiratory chain disorders.por
dc.identifier.citationDev Med Child Neurol. 2007 Oct;49(10):726-33por
dc.identifier.issn0012-1622
dc.identifier.otherdoi 10.1111/j.1469-8749.2007.00726.
dc.identifier.urihttp://hdl.handle.net/10400.18/327
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherDevelopmental Medicine & Child Neurologypor
dc.relation.publisherversionhttp://onlinelibrary.wiley.com/doi/10.1111/j.1469-8749.2007.00726.x/abstractpor
dc.subjectPerturbações do Desenvolvimento Infantil e Saúde Mentalpor
dc.titleEpidemiology of autism spectrum disorder in Portugal: prevalence, clinical characterization, and medical conditionspor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage733por
oaire.citation.startPage726por
oaire.citation.titleDevelopmental Medicine and Child Neurologypor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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