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Fluctuating temperature modifies heat-mortality association around the globe

2022-03-11Journal article Restricted access
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dc.contributor.authorWu, Yao
dc.contributor.authorWen, Bo
dc.contributor.authorLi, Shanshan
dc.contributor.authorGasparrini, Antonio
dc.contributor.authorTong, Shilu
dc.contributor.authorOvercenco, Ala
dc.contributor.authorUrban, Aleš
dc.contributor.authorSchneider, Alexandra
dc.contributor.authorEntezari, Alireza
dc.contributor.authorVicedo-Cabrera, Ana Maria
dc.contributor.authorZanobetti, Antonella
dc.contributor.authorAnalitis, Antonis
dc.contributor.authorZeka, Ariana
dc.contributor.authorTobias, Aurelio
dc.contributor.authorAlahmad, Barrak
dc.contributor.authorArmstrong, Ben
dc.contributor.authorForsberg, Bertil
dc.contributor.authorÍñiguez, Carmen
dc.contributor.authorAmeling, Caroline
dc.contributor.authorDe la Cruz Valencia, César
dc.contributor.authorÅström, Christofer
dc.contributor.authorHouthuijs, Danny
dc.contributor.authorVan Dung, Do
dc.contributor.authorRoyé, Dominic
dc.contributor.authorIndermitte, Ene
dc.contributor.authorLavigne, Eric
dc.contributor.authorMayvaneh, Fatemeh
dc.contributor.authorAcquaotta, Fiorella
dc.contributor.authorde’Donato, Francesca
dc.contributor.authorSera, Francesco
dc.contributor.authorCarrasco-Escobar, Gabriel
dc.contributor.authorKan, Haidong
dc.contributor.authorOrru, Hans
dc.contributor.authorKim, Ho
dc.contributor.authorHolobaca, Iulian-Horia
dc.contributor.authorKyselý, Jan
dc.contributor.authorMadureira, Joana
dc.contributor.authorSchwartz, Joel
dc.contributor.authorKatsouyanni, Klea
dc.contributor.authorHurtado-Diaz, Magali
dc.contributor.authorRagettli, Martina S.
dc.contributor.authorHashizume, Masahiro
dc.contributor.authorPascal, Mathilde
dc.contributor.authorde Sousa Zanotti Stagliorio Coélho, Micheline
dc.contributor.authorScovronick, Noah
dc.contributor.authorMichelozzi, Paola
dc.contributor.authorGoodman, Patrick
dc.contributor.authorNascimento Saldiva, Paulo Hilario
dc.contributor.authorAbrutzky, Rosana
dc.contributor.authorOsorio, Samuel
dc.contributor.authorDang, Tran Ngoc
dc.contributor.authorColistro, Valentina
dc.contributor.authorHuber, Veronika
dc.contributor.authorLee, Whanhee
dc.contributor.authorSeposo, Xerxes
dc.contributor.authorHonda, Yasushi
dc.contributor.authorBell, Michelle L.
dc.contributor.authorGuo, Yuming
dc.date.accessioned2023-01-16T16:03:11Z
dc.date.available2023-01-16T16:03:11Z
dc.date.issued2022-03-11
dc.descriptionFree PMC article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942841/pt_PT
dc.description.abstractStudies have investigated the effects of heat and temperature variability (TV) on mortality. However, few assessed whether TV modifies the heat-mortality association. Data on daily temperature and mortality in the warm season were collected from 717 locations across 36 countries. TV was calculated as the standard deviation of the average of the same and previous days' minimum and maximum temperatures. We used location-specific quasi-Poisson regression models with an interaction term between the cross-basis term for mean temperature and quartiles of TV to obtain heat-mortality associations under each quartile of TV, and then pooled estimates at the country, regional, and global levels. Results show the increased risk in heat-related mortality with increments in TV, accounting for 0.70% (95% confidence interval [CI]: -0.33 to 1.69), 1.34% (95% CI: -0.14 to 2.73), 1.99% (95% CI: 0.29-3.57), and 2.73% (95% CI: 0.76-4.50) of total deaths for Q1-Q4 (first quartile-fourth quartile) of TV. The modification effects of TV varied geographically. Central Europe had the highest attributable fractions (AFs), corresponding to 7.68% (95% CI: 5.25-9.89) of total deaths for Q4 of TV, while the lowest AFs were observed in North America, with the values for Q4 of 1.74% (95% CI: -0.09 to 3.39). TV had a significant modification effect on the heat-mortality association, causing a higher heat-related mortality burden with increments of TV. Implementing targeted strategies against heat exposure and fluctuant temperatures simultaneously would benefit public health.pt_PT
dc.description.abstractPublic summary: Increased temperature variability (TV) poses a greater mortality risk due to heat; TV has a more profound modification effect on extreme heat-mortality association; Strategies against heat and TV simultaneously would benefit public healt.pt_PT
dc.description.sponsorshipThis study was supported by the Australian Research Council (DP210102076) and the Australian National Health and Medical Research Council (APP2000581). Y.W and B.W. were supported by the China Scholarship Council (nos. 202006010044 and 202006010043); S.L. was supported by an Emerging Leader Fellowship of the Australian National Health and Medical Research Council (no. APP2009866); Y.G. was supported by Career Development Fellowship (no. APP1163693) and Leader Fellowship (no. APP2008813) of the Australian National Health and Medical Research Council; J.K. and A.U. were supported by the Czech Science Foundation (project no. 20–28560S); N.S. was supported by the National Institute of Environmental Health Sciences-funded HERCULES Center (no. P30ES019776); Y.H. was supported by the Environment Research and Technology Development Fund (JPMEERF15S11412) of the Environmental Restoration and Conservation Agency; M.d.S.Z.S.C. and P.H.N.S. were supported by the São Paulo Research Foundation (FAPESP); H.O. and E.I. were supported by the Estonian Ministry of Education and Research (IUT34–17); J.M. was supported by a fellowship of Fundação para a Ciência e a Tecnlogia (SFRH/BPD/115112/2016); A.G. and F.S. were supported by the Medical Research Council UK (grant ID MR/R013349/1), the Natural Environment Research Council UK (grant ID NE/R009384/1), and the EU’s Horizon 2020 project, Exhaustion (grant ID 820655); A.S. and F.d.D. were supported by the EU’s Horizon 2020 project, Exhaustion (grant ID 820655); V.H. was supported by the Spanish Ministry of Economy, Industry and Competitiveness (grant ID PCIN-2017–046); and A.T. by MCIN/AEI/10.13039/501100011033 (grant CEX2018-000794-S).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInnovation (Camb) . 2022 Mar 29;3(2):100225. doi: 10.1016/j.xinn.2022.100225. eCollection 2022 Mar 11.pt_PT
dc.identifier.doi10.1016/j.xinn.2022.100225pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/8441
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier/ Cell Presspt_PT
dc.relationEarly life exposure to atmospheric air pollutants and potential DNA damage: Consequences on development and childhood outcomes APPEAL
dc.relationExposure to heat and air pollution in EUrope – cardiopulmonary impacts and benefits of mitigation and adaptation
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S2666675822000212?via%3Dihubpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectHeatpt_PT
dc.subjectModification Effectpt_PT
dc.subjectMortalitypt_PT
dc.subjectTemperature Variabilitypt_PT
dc.subjectAvaliação do Riscopt_PT
dc.titleFluctuating temperature modifies heat-mortality association around the globept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleEarly life exposure to atmospheric air pollutants and potential DNA damage: Consequences on development and childhood outcomes APPEAL
oaire.awardTitleExposure to heat and air pollution in EUrope – cardiopulmonary impacts and benefits of mitigation and adaptation
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F115112%2F2016/PT
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/820655/EU
oaire.citation.issue2pt_PT
oaire.citation.startPage100225pt_PT
oaire.citation.titleThe Innovationpt_PT
oaire.citation.volume3pt_PT
oaire.fundingStreamH2020
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameEuropean Commission
rcaap.embargofctAcesso de acordo com página web do editor da revista.pt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication0c38fa63-8890-47d4-b3d3-1aa47f53b966
relation.isProjectOfPublication59609b8b-2750-43e0-8fe9-155a4915a572
relation.isProjectOfPublication.latestForDiscovery59609b8b-2750-43e0-8fe9-155a4915a572

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