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Aspergillus collected in specific indoor settings: their molecular identification and susceptibility pattern

dc.contributor.authorSimões, Daniela
dc.contributor.authorAranha Caetano, Liliana
dc.contributor.authorVeríssimo, Cristina
dc.contributor.authorViegas, Carla
dc.contributor.authorSabino, Raquel
dc.date.accessioned2020-04-21T18:55:30Z
dc.date.available2020-04-21T18:55:30Z
dc.date.issued2019-08-13
dc.description.abstractExposure to Aspergillus conidia is an increased risk factor for the development of respiratory symptoms. The emergence of azole resistance in Aspergillus fumigatus is a major concern for the scientific community. The aim of this study was to perform the molecular identification of Aspergillus species collected from different occupational and non-occupational indoor settings and to study the azole susceptibility profile of the collected Fumigati isolates. The selected Aspergillus isolates were identified as belonging to the sections Fumigati, Nigri Versicolores, Terrei, Clavati and Nidulantes. All the Aspergillus fumigatus were screened for azole resistance using an agar media supplemented with itraconazole, voriconazole and posaconazole. None of the tested isolates showed resistance to those azoles. Knowledge of Aspergillus epidemiology in specific indoor environments allows a better risk characterization regarding Aspergillus burden. This study allowed the analysis of the molecular epidemiology and the determination of the susceptibility pattern of Aspergillus section Fumigati found in the studied indoor settings.pt_PT
dc.description.sponsorshipThis work was supported by FCT – Fundação para Ciência e Tecnologia under the project EXPOsE – Establishing protocols to assess occupational exposure to microbiota in clinical settings (02/SAICT/2016 – Grant nº 23222).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInt J Environ Health Res. 2019 Aug 13;1-10. doi: 10.1080/09603123.2019.1650903. Online ahead of printpt_PT
dc.identifier.doi10.1080/09603123.2019.1650903pt_PT
dc.identifier.issn0960-3123
dc.identifier.urihttp://hdl.handle.net/10400.18/6473
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francis/ International Federation of Environmental Healthpt_PT
dc.relation.publisherversionhttps://www.tandfonline.com/doi/full/10.1080/09603123.2019.1650903pt_PT
dc.subjectAspergilluspt_PT
dc.subjectOccupational Exposurept_PT
dc.subjectMolecular Epidemiologypt_PT
dc.subjectAntifungal Susceptibilitypt_PT
dc.subjectIndoor Airpt_PT
dc.subjectInfecções Respiratóriaspt_PT
dc.titleAspergillus collected in specific indoor settings: their molecular identification and susceptibility patternpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage10pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleInternational Journal of Environmental Health Researchpt_PT
rcaap.embargofctDe acordo com política editorial da revista.pt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT

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