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Urinary biomonitoring in firefighters: baseline data of polycyclic aromatic hydrocarbons metabolites
Publication . Barros, B.; Oliveira, M.; Paiva, M.; Fernandes, A.; Alves, S.; Vaz, J.; Esteves, F.; Slezakova, K.; Alves, M.J.; Madureira, J.; Pereira, M.C.; Morais, S.
Polycyclic aromatic hydrocarbons (PAHs) are among the most relevant pollutants in the
firefighting context and urine the most straightforward and interesting matrix for
biomonitoring. Recent studies have found elevated levels of PAH metabolites in firefighters
in comparison to the general population. Since Portuguese firefighters are poorly
characterized, the aim of this study was to determine the baseline data (i.e., with no recent
exposure to fire emissions) of several urinary monohydroxyl-PAHs (OHPAHs; 1-hydroxynaphthalene, 1-hydroxyacenaphthene, 2-hydroxyfluorene, 1-hydroxyphenanthrene, 1-
hydroxypyrene, 3-hydroxybenzo(a)pyrene) in this occupational group. A total of 106
Portuguese firefighters were enrolled in this study and characterized through a previously
validated questionnaire. Individual OHPAHs were detected with a frequency of 90-99%,
except for 3-hydroxybenzo(a)pyrene (biomarker of exposure to carcinogenic PAHs) that was
not identified. The individual levels of 1-hydroxypyrene (the established biomarker for PAHs
exposure) were lower than the recommended biological exposure limit proposed by the
American Conference of Governmental Industrial Hygienists (0.93 µmol/mol creatinine).
This study characterized the baseline data of PAHs exposure in Portuguese firefighters by
urinary biomonitoring, which enables comparison with occupational studies from other
countries and contributes to fill a research gap in Portugal
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Fundação para a Ciência e a Tecnologia
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CEEC IND 2017
Número da atribuição
CEECIND/03666/2017/CP1427/CT0007