Browsing by Author "Rodrigues, V."
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- Epidemiology of autism spectrum disorder in Portugal: prevalence, clinical characterization, and medical conditionsPublication . Oliveira, G.; Ataíde, A.; Marques, C.; Miguel, T.S.; Coutinho, A.M.; Mota-Vieira, L.; Gonçalves, E.; Lopes, N.M.; Rodrigues, V.; Carmona da Mota, H.; Vicente, A.M.The objective of this study was to estimate the prevalence of autistic spectrum disorder (ASD) and identify its clinical characterization, and medical conditions in a paediatric population in Portugal. A school survey was conducted in elementary schools, targeting 332,808 school-aged children in the mainland and 10,910 in the Azores islands. Referred children were directly assessed using the Diagnostic and Statistical Manual of Mental Disorders (4th edn), the Autism Diagnostic Interview-Revised, and the Childhood Autism Rating Scale. Clinical history and a laboratory investigation was performed. In parallel, a systematic multi-source search of children known to have autism was carried out in a restricted region. The global prevalence of ASD per 10,000 was 9.2 in mainland, and 15.6 in the Azores, with intriguing regional differences. A diversity of associated medical conditions was documented in 20%, with an unexpectedly high rate of mitochondrial respiratory chain disorders.
- Hepatic steatosis in an adult population: stronger correlation with the presence of obesity and insulin resistence than with the dietary pattern: results from a cross-sectional studyPublication . Leitao, J.A.M.C.P.; Cochicho, J.; Carvalhana, S.; Velasco, F.; Silva, A.P.; Medeiros, I.S.; Alves, A.C.; Bourbon, M.; Oliveiros, B.; Rodrigues, V.; Carvalho, A.; Cortez-Pinto, H.Background and Aims: Hepatic steatosis is very frequent in thegeneral population, mostly associated with obesity and insulinresistance. Typical dietary patterns have been difficult to identifywith controversial information. We aimed to estimate in a represen-tative sample of the Portuguese adult population, what was thecontribution of the dietary pattern in what concerns macronutrientsand food groups for the presence of steatosis as well as the othertraditional risk factors for steatosis.
- Prevalence of alcoholic steatosis in the general adult Portuguese populationPublication . Leitao, J.A.M.C.P.; Carvalhana, S.; Cochicho, J.; Silva, A.P.; Velasco, F.; Medeiros, I.S.; Alves, A.C.; Bourbon, M.; Oliveiros, B.; Rodrigues, V.; Carvalho, A.; Cortez-Pinto, H.Background and Aims: Fatty liver is very frequent in the general population. Although many studies evaluated the prevalence of nonalcoholic fatty liver disease there is scarce information regarding alcoholic fatty liver. We aimed to estimate the prevalence of alcoholic hepatic steatosis, and to what extent it depended on obesity and its interaction.