Percorrer por autor "Kolossa-Gehring, M."
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- A roadmap for a 21st century human biomonitoring toolboxPublication . Zare Jeddi, Maryam; Conrad, A.; Kolossa-Gehring, M.; Hopf, N.; Viegas, S.; Pasanen-Kase, R.; Sepai, O.; Galea, K.S.; Cubadda, F.; Louro, Henriqueta; Silva, Maria João; Nieuwenhuyse, A.V.; Santonen, T.; Scheepers, P.Current challenges in data comparability, integration, and management, hinder effective utilization of the large amount of data generated in environment and health studies. The European chapter of the International Society of Exposure Science (ISES Europe) Human Biomonitoring (HBM) Working Group is developing a global preregistration platform “FAIR Environment and Health Registry (FAIREHR)” to address these challenges. The focus is initially on the HBM domain, towards the implementation of FAIR (findable, accessible, interoperable, reusable) principles throughout the data lifecycle. Preregistration of HBM studies in a peer review-based registry like FAIREHR would stimulate communication and interaction among HBM communities leading to improved HBM study designs as well as generating comparable results worldwide. Using common standards and ontologies will make data better interoperable and functional for machine discovery. FAIREHR will also provide information on data licenses and request procedures necessary to access datasets of interest. Overall, the FAIREHR platform gathers many stakeholders (scientists, regulators, policy makers, life science companies, publishers, and funding bodies) interested in tracking and identifying planned, ongoing, and completed studies. FAIREHR is expected to benefit research, innovation and environment and public health policies by providing FAIR data that can be readily utilized for protecting human health.
- A walk in the PARC: developing and implementing 21st century chemical risk assessment in EuropePublication . Marx-Stoelting, P.; Rivière, G.; Luijten, M.; Aiello-Holden, K.; Bandow, N.; Baken, K.; Cañas, A.; Castano, A.; Denys, S.; Fillol, C.; Herzler, M.; Iavicoli, I.; Karakitsios, S.; Klanova, J.; Kolossa-Gehring, M.; Koutsodimou, A.; Lobo Vicente, J.; Lynch, I.; Namorado, S.; Norager, S.; Pittman, A.; Rotter, S.; Sarigiannis, D.; Silva, M. J.; Theunis, J.; Tralau, T.; Uhl, M.; Van Klaveren, J.; Wendt-Rasch, L.; Westerholm, E.; Rousselle, C.; Sanders, P.Current approaches for the assessment of environmental and human health risks due to exposure to chemical substances have served their purpose reasonably well. Nevertheless, the systems in place for different uses of chemicals are faced with various challenges, ranging from a growing number of chemicals to changes in the types of chemicals and materials produced. This has triggered global awareness of the need for a paradigm shift, which in turn has led to the publication of new concepts for chemical risk assessment and explorations of how to translate these concepts into pragmatic approaches. As a result, next-generation risk assessment (NGRA) is generally seen as the way forward. However, incorporating new scientific insights and innovative approaches into hazard and exposure assessments in such a way that regulatory needs are adequately met has appeared to be challenging. The European Partnership for the Assessment of Risks from Chemicals (PARC) has been designed to address various challenges associated with innovating chemical risk assessment. Its overall goal is to consolidate and strengthen the European research and innovation capacity for chemical risk assessment to protect human health and the environment. With around 200 participating organisations from all over Europe, including three European agencies, and a total budget of over 400 million euro, PARC is one of the largest projects of its kind. It has a duration of seven years and is coordinated by ANSES, the French Agency for Food, Environmental and Occupational Health & Safety.