Browsing by Author "Fouillet, A."
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- European all-cause excess and influenza-attributable mortality in the 2017/18 season: should the burden of influenza B be reconsidered?Publication . Nielsen, Jens; Vestergaard, Lasse; Richter, L.; Schmid, D.; Bustos, N.; Asikainen, T.; Trebbien, R.; Denissov, G.; Innos, K.; Virtanen, M.J.; Fouillet, A.; Lytras, T.; Gkolfinopoulou, K.; Heiden, M. an der; Grabenhenrich, L.; Uphoff, H.; Paldy, A.; Bobvos, J.; Domegan, L.; O'Donnell, J.; Scortichini, M.; de Martino, A.; Mossong, J.; England, K.; Melillo, J.; van Asten, L.; de Lange, M. MA; Tønnessen, R.; White, R.A.; Silva, Susana Pereira; Rodrigues, Ana Paula; Larrauri, Amparo; Mazagatos, Clara; Farah, A.; Carnahan, A.D.; Junker, C.; Sinnathamby, M.; Pebody, R.G.; Andrews, N.; Reynolds, A.; McMenamin, J.; Brown, C.S.; Adlhoch, C.; Penttinen, P.; Mølbak, K.; Krause, T.G.Objectives: Weekly monitoring of European all-cause excess mortality, the EuroMOMO network, observed high excess mortality during the influenza B/Yamagata dominated 2017/18 winter season, especially among elderly. We describe all-cause excess and influenza-attributable mortality during the season 2017/18 in Europe. Methods: Based on weekly reporting of mortality from 24 European countries or sub-national regions, representing 60% of the European population excluding the Russian and Turkish parts of Europe, we estimated age stratified all-cause excess morality using the EuroMOMO model. In addition, age stratified all-cause influenza-attributable mortality was estimated using the FluMOMO algorithm, incorporating influenza activity based on clinical and virological surveillance data, and adjusting for extreme temperatures. Results: Excess mortality was mainly attributable to influenza activity from December 2017 to April 2018, but also due to exceptionally low temperatures in February-March 2018. The pattern and extent of mortality excess was similar to the previous A(H3N2) dominated seasons, 2014/15 and 2016/17. The 2017/18 overall all-cause influenza-attributable mortality was estimated to be 25.4 (95%CI 25.0-25.8) per 100,000 population; 118.2 (116.4-119.9) for persons aged 65. Extending to the European population this translates into over-all 152,000 deaths. Conclusions: The high mortality among elderly was unexpected in an influenza B dominated season, which commonly are considered to cause mild illness, mainly among children. Even though A(H3N2) also circulated in the 2017/18 season and may have contributed to the excess mortality among the elderly, the common perception of influenza B only having a modest impact on excess mortality in the older population may need to be reconsidered.
- Excess mortality among the elderly in 12 European countries, February and March 2012Publication . Mazick, A.; Gergonne, B.; Nielsen, J.; Wuillaume, F.; Virtanen, M.J.; Fouillet, A.; Uphoff, H.; Sideroglou, T.; Paldy, A.; Oza, A.; Nunes, Baltazar; Flores-Segovia, V.M.; Junker, C.; McDonald, S.A.; Green, H.K.; Pebody, R.; Mølbak, K.In February and March 2012, excess deaths among the elderly have been observed in 12 European countries that carry out weekly monitoring of all-cause mortality. These preliminary data indicate that the impact of influenza in Europe differs from the recent pandemic and post-pandemic seasons. The current excess mortality among the elderly may be related to the return of influenza A(H3N2) virus, potentially with added effects of a cold snap.
- Excess mortality among the elderly in european countries, December 2014 to February 2015Publication . Mølbak, K.; Espenhain, L.; Nielsen, J.; Tersago, K.; Bossuyt, N.; Denissov, G.; Baburin, A.; Virtanen, M.; Fouillet, A.; Sideroglou, T.; Gkolfinopoulou, K.; Paldy, A.; Bobvos, J.; van Asten, L.; de Lange, M.; Nunes, Baltazar; Silva, Susana Pereira; Larrauri, A.; Gómez, I.L.; Tsoumanis, A.; Junker, C.; Green, H.; Pebody, R.; McMenamin, J.; Reynolds, A.; Mazick, A.Since December 2014 and up to February 2015, the weekly number of excess deaths from all-causes among individuals ≥ 65 years of age in 14 European countries have been significantly higher than in the four previous winter seasons. The rise in unspecified excess mortality coincides with increased proportion of influenza detection in the European influenza surveillance schemes with a main predominance of influenza A(H3N2) viruses seen throughout Europe in the current season, though cold snaps and other respiratory infections may also have had an effect.
