Browsing by Author "Filipe, Rita"
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- Botulism disguised as parotitisPublication . Caldas, João Paulo; Filipe, Rita; Queirós, Rita; Grilo Novais, António; Almeida, Francisco; Malheiro, Luís; Teixeira Lopes, Teresa; Saraiva, Margarida; Tavares, Margarida; Sarmento, AntónioBotulism is an acute toxin-mediated neuroparalytic syndrome caused by some Clostridium species. It typically presents itself as an acute symmetric descending paralysis of cranial and peripheral nerves, which can potentially evolve to respiratory failure and death. We report a case of botulism diagnosed in a patient presenting with a parotitis probably due to xerostomia, even though he had already sought medical assistance for blurred vision and dysphagia. The neurological symptoms resolved without administration of antitoxin and botulism diagnosis was confirmed with identification of both toxins B and F in patient's serum. We aim to illustrate the need for a high clinical suspicion for the diagnosis of botulism and to report an atypical case of botulism with the production of toxins B and F, the latter being of rare occurrence.
- Change in the Prevalence and Social Patterning of First- and Second-Hand Smoking in PORTUGAL: a Repeated Cross-Sectional Study (2005 and 2014)Publication . Alves, Joana; Filipe, Rita; Machado, João; Nunes, Baltazar; Perelman, JulianBetween 2005 and 2007, important reinforcements of the tobacco legislation have been implemented in Portugal, which may have affected smoking patterns. The aim of this study was to measure the change in prevalence of first- and second-hand smoking (SHS) among adults, and its socio-demographic patterning in Portugal from 2005 to 2014. Data from the last two Portuguese National Health Interview Surveys (2005 and 2014) were used. The changes in daily smoking and SHS were measured using Poisson regressions, stratifying by sex and survey year. The inequalities were measured using relative inequality indexes (RII). From 2005 to 2014, there was a reduction in SHS (75%-54% among men, and 52%-38% among women), and a reduction in smoking among men (27%-26%), and an increase among women (9%-12%). SHS reduction was more marked among less privileged people. Among Portuguese men, inequalities in daily smoking have increased slightly, while among women the gap favoring low-educated reduced. Between 2005 and 2014, SHS decreased, but not daily smoking, particularly among women. Additionally, socioeconomic inequalities in smoking increased. Future policies should simultaneously tackle smoking and SHS prevalence, and their socioeconomic patterning. More comprehensive policies such as comprehensive national (non-partial) bans, combined with price increases could be more effective.
- Schizophyllum commune sphenoidal sinusitis as presentation of a non-Hodgkin LymphomaPublication . Filipe, Rita; Caldas, João Paulo; Soares, Neuza; Sabino, Raquel; Veríssimo, Cristina; Silva, Roberto; Silva-Pinto, André; Tavares, Margarida; Sarmento, AntónioSchizophyllum commune is a basidiomycetes worldwide distributed that has emerged as cause of invasive infections in immunosuppressed patients. We present a case of a man who was simultaneously diagnosed with a small cell non-Hodgkin lymphoma and a sphenoid sinusitis by S. commune. Intraoperative observation and histology description were crucial to consider an alternative diagnosis to mucormycosis suggested by the MRI. The diagnosis was made based on PCR identification and sequencing.