Browsing by Author "Dong, Y."
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- Ultrasonography of gallbladder abnormalities due to schistosomiasisPublication . Richter, J.; Azoulay, D.; Dong, Y.; Holtfreter, M.C.; Akpata, R.; Calderaro, J.; El-Scheich, T.; Breuer, M.; Neumayr, A.; Hatz, C.; Kircheis, G.; Botelho, M.C.; Dietrich, C.F.After malaria, schistosomiasis remains the most important tropical parasitic disease in large parts of the world. Schistosomiasis has recently re-emerged in Southern Europe. Intestinal schistosomiasis is caused by most Schistosoma (S.) spp. pathogenic to humans and leads to chronic inflammation and fibrosis of the colon as well as to liver fibrosis. Gallbladder abnormalities usually occur in patients with advanced hepatic portal fibrosis due to Schistosoma mansoni infection. Occasionally, gallbladder abnormalities have been seen also in children and occurring without associated overt liver abnormalities.The specific S. mansoni-induced gallbladder abnormalities detectable by ultrasound include typical hyperechogenic wall thickening with external gallbladder wall protuberances. The luminal wall surface is smooth. The condition is usually clinically silent although some cases of symptomatic cholecystitis have been described. The ultrasonographic Murphy response is negative. Gallbladder contractility is impaired but sludge and calculi occur rarely. Contrary to other trematodes such as liver flukes, S. mansoni does not obstruct the biliary tract. Advanced gallbladder fibrosis is unlikely to reverse after therapy.
- Ultrasound assessment of schistosomiasisPublication . Richter, J.; Botelho, M.C.; Holtfreter, M.C.; Akpata, R.; El Scheich, T.; Neumayr, A.; Brunetti, E.; Hatz, C.; Dong, Y.; Dietrich, C.F.In 2000, the World Health Organization (WHO) issued an ultrasound field protocol for assessing the morbidity due to Schistosoma (S.) haematobium and S. mansoni. The experience with this classification has recently been reviewed systematically. The WHO protocol was well accepted worldwide. Here we review the use of ultrasound to assess the morbidity due to schistosomiasis with emphasis on easy, quick, and reproducible ways that can be used in the field. Findings obtained with high-end ultrasound scanners in the hospital setting that might eventually have applications in the field are also described.
