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Exploring the aquatic resistome

dc.contributor.authorRosado, Tânia
dc.contributor.authorManageiro, Vera
dc.contributor.authorBalata, Duarte
dc.contributor.authorMenezes, Carina
dc.contributor.authorFerreira, Eugénia
dc.contributor.authorPaulo, Octávio
dc.contributor.authorCaniça, Manuela
dc.contributor.authorDias, Elsa
dc.date.accessioned2020-06-07T17:03:44Z
dc.date.available2020-06-07T17:03:44Z
dc.date.issued2019-07-03
dc.description.abstractAntibiotic resistance is one of the major problems in public health today since the failure of antibiotherapy has dramatic clinical implications such as the increase of mobility/mortality and of health costs. Antibiotic resistance is a dynamic process since antibiotic-resistant microorganisms, and the corresponding genetic material, flows and disseminates among several settings simultaneously: humans, animals and natural habitats. Water environments are recognized as important pools of antibiotic pollution and antibiotic resistance genes, but the water resistome (collection of all genes responsible for antibiotic resistance in water environments) is far from being characterized. It is well known that antibiotic pollution affects the structure/functioning/diversity of aquatic ecosystems, namely the cyanobacteria community. However, the role of cyanobacteria in the context of antibiotic resistance was never characterized. In this presentation, the aims, the team, the methodologies and the preliminary results of the national project EXPLORAR – Exploring the Aquatic Resistome (PTDC/BIA-BMA/31451/2017), founded by the Portuguese Foundation for Science and Technology (FCT, PT) will be discussed. In this project, we are investigating the contribution of indigenous freshwater organisms (cyanobacteria and bacteria) to water resistome. We expect to identify and characterize ecological niches associated with antibiotic resistance in freshwater environments. This may contribute to define a monitoring strategy to map the antibiotic resistance profiles of national freshwater resources. We expect to contribute to the definition of preventive measures against the dissemination of antibiotic resistance in the environment.pt_PT
dc.description.sponsorshipPTDC/BIA-BMA/31451/2017, founded by the Portuguese Foundation for Science and Technology (FCT, PT)pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/6946
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectCyanobacteriapt_PT
dc.subjectAntibiotic Resistancept_PT
dc.subjectAntibiotic Pollutionpt_PT
dc.subjectAquatic Resistomept_PT
dc.subjectHigh-Throughput Sequencingpt_PT
dc.subjectAgentes Microbianos e Ambientept_PT
dc.subjectResistência aos Antimicrobianospt_PT
dc.titleExploring the aquatic resistomept_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceMúrcia, Espanhapt_PT
oaire.citation.title2º Congreso Iberoamericano – 6º Congreso Ibérico de Cianotoxinas, 3-5 Julio 2919pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT

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