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Immune cells and hepatocytes express glycosylphosphatidylinositol-anchored ceruloplasmin at their cell surface

2011-12-15Journal article Restricted access
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dc.contributor.authorMarques, L.
dc.contributor.authorAuriac, A.
dc.contributor.authorWillemetz, A.
dc.contributor.authorBanha, J.
dc.contributor.authorSilva, B.
dc.contributor.authorCanonne-Hergaux, F.
dc.contributor.authorCosta, L.
dc.date.accessioned2012-01-12T14:35:43Z
dc.date.available2012-01-12T14:35:43Z
dc.date.issued2011-12-15
dc.description.abstractCeruloplasmin is a positive acute-phase protein with both anti- and pro-oxidant activities, thus having still unclear physiological functions in inflammatory processes. Importantly, ceruloplasmin has been implicated in iron metabolism due to its ferroxidase activity, assisting ferroportin on cellular iron efflux. Ceruloplasmin can be expressed as a secreted or as a membrane glycosylphosphatidylinositol-anchored protein (GPI-ceruloplasmin), this latter one being reported as expressed mostly in the brain.por
dc.identifier.citationBlood Cells Mol Dis. 2011 Dec 15. [Epub ahead of print]por
dc.identifier.otherESSN: 1096-0961
dc.identifier.otherdoi:10.1016/j.bcmd.2011.11.005
dc.identifier.urihttp://hdl.handle.net/10400.18/359
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S1079979611002336por
dc.subjectDeterminantes Imunológicos em Doenças Crónicaspor
dc.subjectGPI-ceruloplasminpor
dc.subjectFerroportinpor
dc.subjectLipid raftpor
dc.subjectImmune cellspor
dc.subjectHepatocytespor
dc.subjectIron metabolismpor
dc.subjectDoenças Genéticaspor
dc.titleImmune cells and hepatocytes express glycosylphosphatidylinositol-anchored ceruloplasmin at their cell surfacepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleBlood Cells, Molecules and Diseasespor
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor

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