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Host dispersal shapes the population structure of a tick-borne bacterial pathogen

2019-12-17Journal article Restricted access
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dc.contributor.authorNorte, A.C.
dc.contributor.authorMargos, G.
dc.contributor.authorBecker, N.S.
dc.contributor.authorAlbino Ramos, J.
dc.contributor.authorNúncio, M.S.
dc.contributor.authorFingerle, V.
dc.contributor.authorAraújo, P.M.
dc.contributor.authorAdamík, P.
dc.contributor.authorAlivizatos, H.
dc.contributor.authorBarba, E.
dc.contributor.authorBarrientos, R.
dc.contributor.authorCauchard, L
dc.contributor.authorCsörgő, T.
dc.contributor.authorDiakou, A.
dc.contributor.authorDingemanse, N.J.
dc.contributor.authorDoligez, B.
dc.contributor.authorDubiec, A.
dc.contributor.authorEeva, T.
dc.contributor.authorFlaisz, B.
dc.contributor.authorGrim, T.
dc.contributor.authorHau, M.
dc.contributor.authorHornok, S.
dc.contributor.authorKazantzidis, S.
dc.contributor.authorKováts, D.
dc.contributor.authorKrause, F.
dc.contributor.authorLiterak, I.
dc.contributor.authorMänd, R.
dc.contributor.authorMentesana, L.
dc.contributor.authorMorinay, J.
dc.contributor.authorMutanen, M.
dc.contributor.authorNeto, J.M.
dc.contributor.authorNováková, M.
dc.contributor.authorSanz, J.J.
dc.contributor.authorPascoal da Silva, L.
dc.contributor.authorSprong, H.
dc.contributor.authorTirri, I.S.
dc.contributor.authorTörök, J.
dc.contributor.authorTrilar, T.
dc.contributor.authorTyller, Z.
dc.contributor.authorVisser, M.E.
dc.contributor.authorLopes de Carvalho, I.
dc.date.accessioned2020-04-25T10:59:30Z
dc.date.available2020-04-25T10:59:30Z
dc.date.issued2019-12-17
dc.description.abstractf ticks and their associated pathogens. The life cycle of tick-borne pathogens is complex and their evolutionary ecology is shaped by the interactions with vertebrate hosts and tick vectors (Kurtenbach et al., 2006). This study focused on the ecology and genetic diversity of B. burgdorferi s.l. as a model to investigate the drivers of the population structure and to understand the role of host- associated dispersal on the evolution of tick-borne pathogens. This represents a consequential question in the ecology and evolution of any pathogen. Borrelia burgdorferi s.l. is a bacterial complex of over 20 known genospecies, including the etiologic agents of Lyme borreliosis (Casjens et al., 2011; Margos et al., 2015), whose main vectors are ticks of the genus Ixodes (Eisen & Lane, 2002). These bacteria are widespread in Europe, Asia and North America and are also present in North Africa (Margos, Vollmer, Ogden, & Fish, 2011; Zhioua et al., 1999). Different Borrelia genospecies have different patterns of association with vertebrate reservoir hosts (Humair & Gern, 2000; Kurtenbach, Peacey, et al., 1998) because of the immunological host response, mediated by the action of the host's complement system (Kurtenbach et al., 2002). While B. burgdorferi sensu stricto (s.s.) is a generalist genospecies, Borrelia afzelii is mostly associated with mammalian hosts such as rodents, whereas Borrelia valaisiana, Borrelia garinii and Borrelia turdi are mostly associated with birds (Heylen, 2016; Margos et al., 2011). Because tick vectors cannot move large distances independent of hosts, it has been suggested that host specialization determines the spread and dispersal of B. burgdorferi s.l. genospecies (Kurtenbach et al., 2010; Sonenshine & Mather, 1994). Because birds are both important hosts for some Borrelia genospecies and for various species of vector ticks, they act as a driving force shaping B. burgdorferi s.l. distribution and phylogeographical patterns (Margos et al., 2011; Vollmer et al., 2011). Here, we assessed the role of passerine birds as hosts and dispersers of B. burgdorferi s.l. We tested the hypothesis that infection prevalence with Borrelia genospeciept_PT
dc.description.sponsorshipThis study received financial support from Fundação para a Ciência e a Tecnologia by the strategic program of MARE (MARE - UID/MAR/04292/2013) and the fellowship to Ana Cláudia Norte (SFRH/BPD/108197/2015), and the Portuguese National Institute of Health. Raivo Mänd, Tomi Trilar, Tapio Eeva, Tomas Grim and Dieter Heylen were supported by the Estonian Research Council (research grant # IUT34-8), the Slovenian Research Agency -programme “Communities, relations and communications in the ecosystems” (No. P1-0255), the Academy of Finland (project 265859), the Internal Grant Agency of Palacky University (PrF_2014_018, PrF_2015_018, PrF_2013_018) and the Marie Sklodowska-Curie Actions (EU-Horizon 2020, Individual Global Fellowship, project no 799609), respectively.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMol Ecol 2020 Feb;29(3):485-501. doi: 10.1111/mec.15336. Epub 2019 Dec 17pt_PT
dc.identifier.doi10.1111/mec.15336pt_PT
dc.identifier.issn0962-1083
dc.identifier.urihttp://hdl.handle.net/10400.18/6517
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherJohn Wiley and Sonspt_PT
dc.relationEffects of co-infections on the emergence of an avian disease Mycoplasma gallisepticum
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/abs/10.1111/mec.15336pt_PT
dc.subjectBorrelia gariniipt_PT
dc.subjectLyme borreliosispt_PT
dc.subjectBirdspt_PT
dc.subjectHost-paraste Interationspt_PT
dc.subjectMigrationpt_PT
dc.subjectTickspt_PT
dc.subjectInfecções Sistémicas e Zoonosespt_PT
dc.titleHost dispersal shapes the population structure of a tick-borne bacterial pathogenpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleEffects of co-infections on the emergence of an avian disease Mycoplasma gallisepticum
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/799609/EU
oaire.citation.endPage501pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage485pt_PT
oaire.citation.titleMolecular Ecologypt_PT
oaire.citation.volume29pt_PT
oaire.fundingStreamH2020
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameEuropean Commission
rcaap.embargofctDe acordo com política editorial da revista.pt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication8db1d0b4-c269-4fce-92c5-5e1f5b01a179
relation.isProjectOfPublication.latestForDiscovery8db1d0b4-c269-4fce-92c5-5e1f5b01a179

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