A role for gene-environment interactions in Autism Spectrum Disorder is suggested by an excess of potentially pathogenic variants in genes regulating exposure to toxicants

Santos, J.X.Marques, A.R.Rasga, C.Asif, M.Vilela, J.Martiniano, H.Oliveira, G.Nunes, A.Vicente, A.M.2018-07-132018-07-132018-06http://hdl.handle.net/10400.18/5577Objective: Identify potentially pathogenic CNVs and SNVs targeting genes involved in regulation of toxins exposure, namely in detoxification processes and physiological permeability barriers (blood-brain barrier and placenta), in individuals with ASD.engAutism Spectrum DisorderAutismGenetic FactorsPerturbações do Desenvolvimento Infantil e Saúde MentalA role for gene-environment interactions in Autism Spectrum Disorder is suggested by an excess of potentially pathogenic variants in genes regulating exposure to toxicantsconference object