Silva, VanessaRibeiro, JessicaTeixeira, PedroPinto, PedroVieira-Pinto, MadalenaPoeta, PatríciaCaniça, ManuelaIgrejas, Gilberto2025-02-132025-02-132024-06-20Pathogens. 2024 Jun 20;13(6):519. doi: 10.3390/pathogens13060519http://hdl.handle.net/10400.18/10344(This article belongs to the Special Issue Exploring the Epidemiology, Pathogenicity, and Therapeutic Options of Staphylococcus spp.: 2nd Edition)Sternal bursitis, a common inflammatory condition in poultry, poses significant challenges to both animal welfare and public health. This study aimed to investigate the prevalence, antimicrobial resistance, and genetic characteristics of isolates associated with sternal bursitis in chickens. Ninety-eight samples were collected from affected chickens, and 24 isolates were identified. Antimicrobial susceptibility testing revealed resistance to multiple agents, with a notable prevalence of aminoglycoside resistance genes. Whole genome sequencing elucidated the genetic diversity and virulence profiles of the isolates, highlighting the predominance of clonal complex 5 (CC5) strains. Additionally, biofilm formation assays demonstrated moderate biofilm production capacity among the isolates. These findings underscore the importance of vigilant monitoring and targeted interventions to mitigate the impact of sternal bursitis in poultry production systems.engCC5Staphylococcus aureusAntimicrobial ResistanceBreast BlistersGenetic LineagesPoultryResistência aos Antimicrobianosjournal article10.3390/pathogens130605192076-081738921816