Loureiro, ClaudiaMatos, PauloClarke, LukaJordan, Peter2018-03-052018-03-052017-06-01http://hdl.handle.net/10400.18/5196Protein kinase Syk was recently found to phosphorylate a specific tyrosine residue in three distinct disease-related chloride transport proteins: CFTR (in cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD)), NKCC2 and KCC3 (in kidney function and hypertension).engVias de Transdução de Sinal e Patologias AssociadasWNK Protein KinasesFibrose QuísticaHipertensão ArterialFosforilação TirosinaThe adaptor protein SHC1 is recruited to tyrosine-phosphorylated plasma membrane chloride channelsconference object