Sousa, SusanaAlmeida, AndréDelgado, LurdesConceição, AntóniaMarques, Cláudiada Costa, José Manuel CorreiaCastro, António2021-04-012021-04-012020-05-14Sci Rep. 2020 May 14;10(1):7947. doi: 10.1038/s41598-020-64590-42045-2322http://hdl.handle.net/10400.18/7624Toxoplasma gondii oocyst wall protein 1 (TgOWP1) integrates a family of seven proteins, consensually assumed as specific antigens of Toxoplasma gondii oocyst stage, located in the outer layer of the oocyst wall. Herein, we notice the expression of a recombinant antigen, rTgOWP1-f, derived from a fragment selected on basis of its structural homology with Plasmodium MSP1-19. Rabbit polyclonal antibodies anti-rTgOWP1-f evidence ability for specific identification of environmental T. gondii oocysts. We assume, rTgOWP1-f, as a possible biomarker of oocysts. In addition, we present findings supporting this vision, including the development of an immunodetection method for T. gondii oocysts identification.engAmino Acid SequenceBiomarkersModels, MolecularOocystsProtein ConformationProtozoan ProteinsToxoplasmaInfecções Sistémicas e Zoonosesjournal article10.1038/s41598-020-64590-4