Gomes, B.Molina-Correa, G.Neves-Reina, L.Oliveira, A.C.Macedo, R.Carvalho, C.Correia, A.M.2021-04-052021-04-052020-12Pulmonology. Nov-Dec 2020;26(6):412-414. doi: 10.1016/j.pulmoe.2020.02.006. Epub 2020 Mar 29.http://hdl.handle.net/10400.18/7634Letter to the EditorExtract: In 2017, the notification rate of tuberculosis in the Northern Region of Portugal was 21.1 cases per 100 000 inhabitants. According to the National Tuberculosis Programme Surveillance System (SVIG-TB), poly-resistance to isoniazid and streptomycin (PR-HS) represented 2.6–5% of the cases notified in the Northern Region between 2009 and 2017 Although they represent a relatively low proportion of cases in Portugal, poly-resistances such as PR-HS are precursors to multidrug resistance and, consequently, should be closely monitored.engTuberculosisPortugalInfecções Respiratóriasjournal article10.1016/j.pulmoe.2020.02.006