Asif, M.Martiniano, Hugo F.Rasga, CéliaMarques, Ana R.Santos, João X.Couto, Francisco M.Vicente, Astrid M.2017-12-122017-12-122017-11-14http://hdl.handle.net/10400.18/4851Objectives: The global objective of the study is to improve the current knowledge on ASD prognosis and diagnosis by delineating the complex genotype-phenotype associations using an integrative systems biology approach. For this purpose three specific objectives were pursued: - To identify clinically similar subgroups of individuals with ASD; - To find biological processes disrupted by rare CNVs targeting brain genes in ASD subjects; - To train a machine learning classifier for the clinical prediction of disease progression from genetic information in very young children.engAutism Spectrum DisorderPerturbações do Desenvolvimento Infantil e Saúde MentalAutismoconference object