Henriques, Andreia F.Matos, PauloJordan, Peter2018-03-132018-03-132017-10EMJ Oncol. 2017;5[1]:50-52. Abstract Review No. AR9.2054-619Xhttp://hdl.handle.net/10400.18/5394Reprogramming of energy metabolism is one of the hallmarks of cancer, since tumour cells need to fuel their high proliferation rates. Warburg et al. first observed that cancer cells largely limit their method of energy production to glycolysis only. In order to compensate for lower ATP yields, cancer cells often upregulate expression of glucose transporters, typically GLUT1, which substantially increases extracellular glucose import into the cytoplasm.engWNK Protein KinasesColorectal CancerTumor CellsWNK Proteina CinasesTransporte de GlucoseVias de Transdução de Sinal e Patologias AssociadasCancro Coloretalconference object10.1093/annonc/mdx361.036