Caniça, ManuelaManageiro, VeraJones-Dias, DanielaClemente, LurdesGomes-Neves, EduardaPoeta, PatríciaDias, ElsaFerreira, Eugénia2016-03-232019-10-012015Res Microbiol. 2015 Sep;166(7):594-600. doi: 10.1016/j.resmic.2015.07.009. Epub 2015 Aug 40923-2508http://hdl.handle.net/10400.18/3724This work was presented, in part, as an opening lecture plus a keynote at the TEMPH2014-Trends in Environmental Microbiology for Public Health, Lisbon, PortugaAntibiotic resistance consists of a dynamic web. In this review, we describe the path by which different antibiotic residues and antibiotic resistance genes disseminate among relevant reservoirs (human, animal, and environmental settings), evaluating how these events contribute to the current scenario of antibiotic resistance. The relationship between the spread of resistance and the contribution of different genetic elements and events is revisited, exploring examples of the processes by which successful mobile resistance genes spread across different niches. The importance of classic and next generation molecular approaches, as well as action plans and policies which might aid in the fight against antibiotic resistance, are also reviewed.engResistência aos AntibióticosAntibioticsResistomeMobilomeReservoirsDisseminationjournal article10.1016/j.resmic.2015.07.009