Cardoso, R.Gonçalves, A.da Silva, J.M.Oliveira, C.Xavier, P.Alves, H.Barros, A.Botelho, M.C.2017-11-032017-11-032017-05-08http://hdl.handle.net/10400.18/4800AIM: To study the polymorphic variants in CYP2C9*2*3 and the C-174G promoter polymorphism of the IL-6 gene on Infertile Women.BACKGROUND: - Infertility affects 15–20% of couples worldwide. Within the past decades, there has been a steady rise in the treatment of female infertility with several drugs; - The cytochrome P450 (CYP) genes are oxygenases involved in estrogen biosynthesis and metabolism, generation of DNA damaging procarcinogens, and response to anti-estrogen therapies used in female infertility treatments: - Interleukin-6 (IL-6) is a pleiotropic proinflammatory cytokine, highly expressed in the female urogenital tract and reproductive organs. It has been implicated in estrogen metabolism imbalance.engGenetic VariantsFemale Infertilityconference object